Biochemical and Biophysical Research Communications

Medical research

Awakening dormant cells to fight cancer

The advent of small-molecule targeted therapies, a decade ago, revolutionized the treatment of metastatic melanoma, provided that the tumors carry the mutations to respond to these treatments. However, despite a remarkable ...

Oncology & Cancer

Researchers ID new biomarker for colorectal cancers

Johns Hopkins researchers have identified a protein involved in cell proliferation and the development of new blood vessels that could serve as a marker for the early detection of colorectal cancers.

Medical research

Understanding how bone-dissolving cells are generated

Bone-dissolving cells called osteoclasts are derived from a type of immune cells called macrophages. They are necessary for the maintenance and renewal of bones. But the intracellular mechanisms through which macrophages ...

Oncology & Cancer

Chemists discover a surprising effect of a well-known leukemia drug

Researchers from RUDN University and Institute of Biomedical Chemistry of the Russian Academy of Sciences have identified an alternative mechanism for the effective antitumor drug—an enzyme called L-asparaginase. Some isoenzymes ...

Oncology & Cancer

Boosting sarcoma cell death

Ewing sarcomas – rare, aggressive childhood cancers – are derived from mesenchymal cells in bone and soft tissues, and children with metastatic disease have poor survival.

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