Biological Psychiatry

Neuroscience

Microglial methylation "landscape" in human brain

In the central nervous system, microglial cells play critical roles in development, aging, brain homeostasis, and pathology. Recent studies have shown variation in the gene-expression profile and phenotype of microglia across ...

Psychology & Psychiatry

Star cells in the brain render memory flexible

As we live in a dynamically changing environment, it is important for our brain to not only learn new things but also to modify existing memories. This is commonly referred to as "cognitive flexibility." Without this ability, ...

Psychology & Psychiatry

Addiction relapse driven by drug-seeking habit, not just drug

Why are some individuals able to use recreational drugs in a controlled way, whereas others switch to the compulsive, relapsing drug-seeking and -taking habits that characterize substance use disorder (SUD)? Despite more ...

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