Biological Psychiatry

Psychology & Psychiatry

Study finds neurosteroid deficits lead to depressed behavior

The latest generation of antidepressants relieves symptoms by mimicking steroids produced by the brain to ensure neurons are effectively talking to each other. How these neurosteroids are linked to depression and why they ...

Psychology & Psychiatry

Potential therapeutic target for schizophrenia identified

Targeting calcium signaling in neurons represents a promising therapeutic approach for treating a rare form of schizophrenia, according to a Northwestern Medicine study published in Biological Psychiatry.

Health

Heavy drinking in young adults tied to endocannabinoid pathway

Although heavy drinking in young adulthood increases the risk for alcohol use disorder (AUD), not all young heavy drinkers go on to develop AUD, globally the most common substance use disorder. Research has shown that individual ...

Psychology & Psychiatry

New support for the notion of a serotonin deficit in depression

Since the 1960s, researchers have postulated that major depression stems from disruptions in the serotonin neurotransmitter system, but the evidence for that idea, though plentiful, was indirect. In fact, a recent comprehensive ...

Diseases, Conditions, Syndromes

Study reveals how racism takes its toll on the brain and body

Structural racism has not only psychosocial but also biological consequences. Discrimination has been shown to contribute to mental and physical disorders including obesity, depression, and addiction, but the biological pathways ...

Genetics

New insights into lithium's effectiveness for bipolar disorder

Bipolar disorder, a neuropsychiatric condition that includes manic and depressive episodes, affects about 1% of the population and is strongly influenced by genetics. About half of patients respond very well to lithium salts ...

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