Damage to the autism-associated gene Dyrk1a, sets off a cascade of problems in developing mouse brains, resulting in abnormal growth-factor signaling, undergrowth of neurons, smaller-than-average brain size, and, eventually, ...
Apr 8, 2021
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Since the discovery of leptin in the 1990s, researchers have wondered, how does leptin, a hormone made by body fat, suppress appetite? Despite tremendous gains in the intervening three decades, many questions still remain. ...
Apr 6, 2021
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An analysis of sex differences in the genetics of schizophrenia, bipolar disorder and major depressive disorders indicates that while there is substantial genetic overlap between males and females, there are noticeable sex-dependent ...
Mar 23, 2021
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A major impediment to treatment of substance use disorder (SUD) is a loss of behavioral flexibility, whereby one's judgment is impaired such that their actions continuously result in negative consequences. Such decisions ...
Feb 17, 2021
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Trauma-focused psychotherapy is widely considered the best available treatment for posttraumatic stress disorder (PTSD). However, the ways in which this method affects the brain to promote recovery from PTSD are not well ...
Jan 27, 2021
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Addiction, or substance use disorder (SUD), is a complex neurological condition that includes drug-seeking behavior among other cognitive, emotional and behavioral features. Synaptic plasticity, or changes in the way neurons ...
Jan 26, 2021
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45
Stress on an expectant mother could affect her baby's chance of developing disease—perhaps even over the course of the child's life, UC researchers have found.
Jan 11, 2021
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Researchers at Karolinska Institutet have investigated the association between certain immune markers in neonates and the risk of later developing autism spectrum disorder (ASD). They found that mid-levels of a classical ...
Nov 10, 2020
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Drugs of abuse, like cocaine, are very addictive due in part to their cellular interaction, creating strong cellular memories in the brain that promote compulsive behaviors. Researchers have tried to understand the formation ...
Oct 15, 2020
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117
Depression in elderly people can include symptoms such as memory loss, making it hard to distinguish from the early stages of Alzheimer's disease and other types of dementia. A signature of Alzheimer's is accumulation of ...
Sep 23, 2020
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