Cancer Cell

Medical research

Mathematical model finds the cancer mutations that matter

Researchers have generated a long list of genetic mutations linked to cancer, but sorting out which ones really drive tumors to grow uncontrollably and which ones don't has been a challenge. A new mathematical model developed ...

Oncology & Cancer

How lymphoma cells metastasize to the brain

Lymphomas in the central nervous system are rare but dangerous. Scientists at the German Cancer Research Center (DKFZ) have now discovered which molecular mechanism leads to lymphomas forming metastases in the central nervous ...

Oncology & Cancer

The tumor microenvironment

Cancer researchers are setting their sights on a new kind of cancer treatment that targets the tumor's surrounding environment, called the tumor microenvironment, in contrast to targeting the tumor directly.

Oncology & Cancer

Cracking the code of a brain cancer that keeps coming back

One of the most common brain cancers in children, Sonic Hedgehog (SHH) medulloblastoma, also is one of the more survivable for most kids. Unfortunately, for a subset of patients the cancer resists treatment and relapses with ...

Oncology & Cancer

Major breakthrough in the treatment of leukemia

A molecular process involved in the action of anti-leukemia drugs has been discovered at Université de Montréal's Institute for Research in Immunology and Cancer (IRIC). While calling into question a central tenet of oncology, ...

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