Cancer Cell

Oncology & Cancer

A master switch controls aggressive breast cancer

A team at the Salk Institute has identified a master switch that appears to control the dynamic behavior of tumor cells that makes some aggressive cancers so difficult to treat. The gene Sox10 directly controls the growth ...

Oncology & Cancer

Study indicates possible new way to treat endometrial, colon cancers

Scientists love acronyms. In the quest to solve cancer's mysteries, they come in handy when describing tongue-twisting processes and pathways that somehow allow tumors to form and thrive. Two examples are ERK (extracellular-signal-related ...

Oncology & Cancer

Breast cancer cells in mice tricked into turning into fat cells

As cancer cells respond to cues in their microenvironment, they can enter a highly plastic state in which they are susceptible to transdifferentiation into a different type of cell. Researchers at the University of Basel ...

Oncology & Cancer

Loss of cilia leads to melanoma

Most cells in the human body have a cilium, a slender cell protuberance that picks up signals from the cell's external environment. Researchers at the University of Zurich have now shown that these fine sensory antennae play ...

Oncology & Cancer

Scientists develop potential new class of cancer drugs in lab

In research published in Cancer Cell, Thomas Burris, Ph.D., chair of pharmacology and physiology at Saint Louis University, has, for the first time, found a way to stop cancer cell growth by targeting the Warburg Effect, ...

Medical research

New hope for kidney cancer treatment using existing drugs

The most comprehensive study of kidney cancer at single-cell level has discovered a potential drug target to treat renal cell carcinoma, a cancer with a high mortality rate that is hard to detect. Researchers from the Wellcome ...

Oncology & Cancer

Research uncovers defender against cancer-promoting liver damage

Most cases of liver cancer develop after long-term viral infection, chronic exposure to alcohol, or excessive accumulation of fat in the liver due to obesity. The liver reacts to those insults by trying to wall it off with ...

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