Cancer Discovery is a journal of the American Association for Cancer Research.
Applying the same solution to different problems is a common mistake, not only among humans but also in our immune system. Flooding a wound with inflammation-causing white blood cells can be helpful for fighting infection, ...
May 8, 2023
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The p53 gene is one of the most important in the human genome: the only role of the p53 protein that this gene encodes is to sense when a tumor is forming and to kill it. While the gene was discovered more than four decades ...
May 4, 2023
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Pancreatic ductal adenocarcinoma (PDAC) is the most common form of pancreatic cancer. It's also one of the deadliest. More than 90% of PDAC patients die within five years of diagnosis. Usually, by the time the cancer is identified, ...
Apr 26, 2023
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Despite the promise of new medications that promote cancer cell death in people with acute myeloid leukemia, leukemic cells often adopt features that let them evade the drugs' effects within a year.
Apr 24, 2023
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A new study led by researchers at The University of Texas MD Anderson Cancer Center has discovered that co-occurring mutations in three tumor suppressor genes—KEAP1, SMARCA4 and CDKN2A—are linked with poor clinical outcomes ...
Apr 17, 2023
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Researchers from the National Institutes of Health (NIH) have outlined opportunities for achieving President Biden and First Lady Biden's Cancer Moonshot national goal of reducing the cancer death rate by at least 50% over ...
Apr 17, 2023
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Pancreatic intraepithelial neoplasia (PanIN) lesions were detected in a majority of healthy pancreases from deceased donors of diverse age and harbored features of pancreatic cancer, according to a study published in Cancer ...
Apr 6, 2023
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Scientists have determined how some skin cancers stop responding to treatment at the end of life.
Mar 28, 2023
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Many cancer patients undergo treatment with multiple drugs, each of which attacks cancer in a different way, so the combination fights cancer on many fronts. But more drugs mean higher risks of side effects.
Mar 23, 2023
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Researchers have shown for the first time exactly how immature neutrophils—white blood cells that are an important part of the immune system—are hijacked by pancreatic cancers to drive immunosuppression and treatment ...
Mar 22, 2023
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