Cell Death and Disease

Oncology & Cancer

Protein causes mutations that lead to breast cancer cell aggression

Like most scientists, University of Alberta biochemist Ing Swie Goping is curious. When her team discovered that a protein was associated with poor outcomes in breast cancer patients, she wanted to know why. Now, that curiosity ...

Oncology & Cancer

New combination treatment flips the switch on melanoma cells

Think of the protein BH3 like a finger that turns off a cancer cell survival switch. The problem is that most cancer cells have found ways to remove this "finger—commonly, by breaking the action of a gene called p53 that ...

Diabetes

Scientists identify new gene linked to Type 2 diabetes

Scientists have identified a new gene which appears to play a lead role in triggering the onset of Type 2 diabetes. The study, led by Nottingham Trent University, found that activity of the 'TNFR5' gene significantly increases ...

Medical research

Study offers future hope for tackling signs of ageing

A new advance in biomedical research at the University of Leicester could have potential in the future to assist with tackling diseases and conditions associated with ageing – as well as in treating cancer.

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