Health
Why can't I lose weight?
You've cut back on your eating, started an exercise routine and just can't seem to lose weight. What's going on?
Jan 6, 2023
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Cell Metabolism
Oncology & Cancer
Researchers uncover novel aspect of tumor evolution and potential targets for therapy
A Ludwig Cancer Research study has discovered that the immune system's surveillance of cancer can itself induce metabolic adaptations in the cells of early-stage tumors that simultaneously promote their growth and equip them ...
Jan 5, 2023
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Overweight & Obesity
Timing calorie intake synchronizes circadian rhythms across multiple systems in mice
Numerous studies have shown health benefits of time-restricted eating including increase in life span in laboratory studies, making practices like intermittent fasting a hot topic in the wellness industry. However, exactly ...
Jan 3, 2023
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258
Overweight & Obesity
Microprotein found to increase appetite in mice
Obesity and metabolic diseases, such as diabetes, are extremely common in the United States. Tiny proteins called microproteins have long been overlooked in research, but new evidence demonstrates that they have an important ...
Jan 3, 2023
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82
Oncology & Cancer
Tumor ammonia levels inhibit T cell growth, impact immunotherapy: Study
High levels of ammonia in tumors leads to fewer T cells and immunotherapy resistance in mouse models of colorectal cancer, new findings from the University of Michigan Rogel Cancer Center revealed. Researchers found that ...
Dec 23, 2022
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58
Diseases, Conditions, Syndromes
High fat, low carb: A ketogenic diet could help patients with polycystic kidney disease
A new study has shown that ketosis—a state in which the body primarily uses dietary fats as energy sources—may have positive effects on kidney function in people affected by hereditary polycystic kidney disease.
Nov 8, 2022
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Diabetes
Switching tracks: Changing the trafficking of the glucagon receptor in the liver regulates its metabolic signaling
A group of researchers from the Helmholtz Munich Institute for Diabetes and Cancer (IDC) have unraveled a new strategy to alter glucagon receptor signaling in the liver by changing its intracellular trafficking. Glucagon ...
Oct 18, 2022
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Medications
Findings support repurposing rheumatoid arthritis drug auranofin for diabetes
Researchers at Baylor College of Medicine and collaborating institutions discovered that the rheumatoid arthritis drug auranofin can potentially be repurposed to improve diabetes-associated symptoms. The study, which was ...
Oct 14, 2022
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Medical research
New research details the microbial origins of Type 1 diabetes
Almost a decade ago, UO graduate student Jennifer Hampton Hill made a fortuitous find: A protein made by gut bacteria that triggered insulin-producing cells to replicate. The protein was an important clue to the biological ...
Oct 13, 2022
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Diseases, Conditions, Syndromes
Hormone protects against development of fatty liver
A group at MedUni Vienna has identified a regulatory loop controlled by leptin, by which this adipocyte-derived hormone regulates hepatic lipid metabolism via the autonomic nervous system. The study, published in Cell Metabolism, ...
Oct 11, 2022
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