Clinical Cancer Research

Oncology & Cancer

Revising theory of cancer-induced immune suppression

Many cancers produce an enzyme called IDO that suppresses immune system activity, but the long-held hypothesis of how this mechanism operates requires revision, according to a study published in Clinical Cancer Research.

Oncology & Cancer

Studying resistance to therapy in BRAF-mutated brain tumors

Looking to understand why some brain tumors with a specific mutation can start to reject drugs commonly used to treat them, CU Cancer Center member Jean Mulcahy Levy, MD, led researchers from institutions around the country—including ...

Oncology & Cancer

Possible viable treatment for human brain cancer

A team of researchers at Texas A&M University, Northwestern University, and ImmunoGenesis has discovered a treatment for glioblastoma that has promising implications for the human version of the aggressive cancer form that ...

Oncology & Cancer

Uncovering epigenetic mechanisms regulating glioma growth

Northwestern Medicine investigators have discovered the epigenetic mechanisms involved in the regulation of multiple oncogenes in glioma cells, mechanisms that promote overall glioma tumor growth and resistance to therapy, ...

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