Disease Models & Mechanisms

Disease Models & Mechanisms (DMM) is a biomedical research journal committed to presenting highly significant research providing insight into disease mechanisms, diagnostics and treatment. The journal aspires to promote the development of new ideas, projects and collaborations among basic researchers, translational researchers, and clinicians. DMM also provides expert reviews and commentaries on key findings in the field, as well as clinical perspectives and challenges. As with other journals published by the Company of Biologists - Development, Journal of Cell Science and The Journal of Experimental Biology - DMM aims to provide strong support for our authors and great quality and breadth of published content to our readers.

Publisher
The Company of Biologists
Impact factor
4.584 (2010)

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Alzheimer's disease & dementia

Tiny worm mimics key genetic risk for Alzheimer's

Researchers at The University of Alabama have shown a tiny worm can replicate genetic causes of Alzheimer's disease, expanding the breadth of preclinical models for the disease.

Diabetes

Diabetes-associated pain linked to disrupted insulin signalling

The chronic pain experienced by a number of patients with diabetes has widely been assumed to originate from damage to blood vessels or to local tissue surrounding neurons caused by high blood-sugar levels. However, a new ...

Medical research

Scientists search for the clocks behind aging brain disorders

To understand the link between aging and neurodegenerative disorders such as Alzheimer's disease, scientists from the National Institutes of Health compared the genetic clocks that tick during the lives of normal and mutant ...

Medical research

Early intervention may hold key to treatment of Friedreich's ataxia

Current treatments may be administered too late to target Friedreich's ataxia effectively. New research using a slow-onset frataxin knock-in/knockout mouse model showed significantly reduced levels of mitochondrial biosynthesis ...

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