A powerful immune molecule helps protect transplanted organs from rejection by putting a silencer on two other immune molecules that converge to take a direct shot at the organ, scientists report.
Feb 5, 2019
0
5
AICAr (5-amino-4-imidazolecarboxamide riboside, also called Acadesine) has been found to inhibit cell proliferation and has cytotoxic potential for childhood acute lymphoblastic leukemia (ALL) cells. Much of the drug's cytotoxic ...
Jan 31, 2019
0
1
Despite the strong association between diabetes and dementia, how insulin deficiency affects brain function remains unclear. A recent study published in The FASEB Journal used a mouse model to investigate this mechanism.
Jan 24, 2019
0
2
Recent studies have shown that maternal gut microbiota in humans primes the offspring's immune and metabolic development during pregnancy and lactation. Due to environmental factors that are impractical to control in human ...
Jan 17, 2019
0
0
A study published in The FASEB Journal demonstrated that dietary supplementation with omega-3 fatty acids (or fish oils) reduced the rate at which young women lost muscle mass during a period of immobilization.
Jan 10, 2019
0
6
Melanoma skin cancer tumors grow larger and are more likely to metastasize due to interactions between a pair of molecules, according to experiments in mice and human cells. The results may restore the potential for a type ...
Nov 21, 2018
0
176
A recent animal study published in The FASEB Journal explores the uncharted territory of how the gut microbiome develops in infancy. It was well known that breast-fed mouse pups have a simple bacterial population dominated ...
Nov 15, 2018
0
3
Cell-penetrating peptides (CPPs) have attracted great interest as delivery vehicles in medicine, with potential for the development of novel therapeutic agents or cosmetic products. Biological membranes are typically impermeable ...
A recent study published in The FASEB Journal examined the effect of young plasma on aged livers, and livers' sensitivity to ischemia reperfusion injury (IRI) in experimental animals. IRI occurs when blood flow to an organ ...
Nov 1, 2018
0
1
For decades, metformin has been the first-line drug for the treatment of type 2 diabetes, lowering blood glucose levels by inhibiting glucose production in the liver. Metformin also improves glucose uptake and use by muscle ...
Oct 23, 2018
0
17
