Immunity

Diseases, Conditions, Syndromes

Mechanisms underlying autoimmunity in Down syndrome revealed

Scientists at the Icahn School of Medicine at Mount Sinai in New York have identified which parts of the immune system go awry and contribute to autoimmune diseases in individuals with Down syndrome. The findings published ...

Genetics

How genes can affect antibodies against SARS-CoV-2

Ph.D. student Pradeepa Pushparaj, in Gunilla Karlsson Hedestams group at the Department of Microbiology, Tumor and Cell Biology, is the first author of a study recently published in Immunity.

Oncology & Cancer

Why lung cancer doesn't respond well to immunotherapy

Immunotherapy—drug treatment that stimulates the immune system to attack tumors—works well against some types of cancer, but it has shown mixed success against lung cancer.

Immunology

Study reframes understanding of graft-versus-host disease

New research challenges the prevailing hypothesis for how donor stem cell grafts cause graft-versus-host disease, or GVHD, and offers an alternative model that could guide development of novel therapies.

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