Researchers at Karolinska Institutet in Sweden have studied which genes are expressed in overactive immune cells in mice with asthma-like inflammation of the airways. Their results, which are published in the journal Immunity, ...
Jun 27, 2019
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Early exposure to antibiotics can trigger long term susceptibility to asthma, according to new research from Monash University. Importantly, the research team isolated a molecule produced by gut bacteria that in the future ...
Jul 15, 2024
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Neutrophils are the warriors of the immune system. They are always ready to spring to action to help heal injuries or fight off disease. Unless, that is, something goes wrong in their developmental process.
Aug 18, 2020
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Imagine developing a drug designed to inhibit a protein that helps cancer cells proliferate and survive only to find that the drug does not perform very well in the clinic. This was the dilemma faced by scientists researching ...
Feb 16, 2016
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Memory T cells are a critical element of our immune system's historical archive. To prevent repeat infections, these cells retain a record of germs they've fought before.
Apr 17, 2018
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Respiratory viral infections pose significant morbidity and mortality to patients with chronic lung diseases like emphysema and COPD, causing exacerbations that drive destruction of normal lung tissue, and leading to one ...
Feb 23, 2023
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Immunoglobulin G antibodies (IgB) play an important role as drivers of inflammation in infectious diseases and autoimmune diseases. However, if the same immunoglobulin antibodies from the blood plasma of healthy donors are ...
May 10, 2023
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Intestinal epithelial cells line the inner wall of the gut, creating a barrier to dangerous bacteria like enteropathogenic E. coli that seek to attach and efface that barrier, causing diarrhea. Such pathogens pose significant ...
Apr 8, 2022
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So-called "hot" tumors filled with T cells are often considered to be more sensitive to immunotherapy compared to "cold" tumors with fewer T cells, but a clear demonstration of why has eluded cancer biologists—until now. ...
Jun 28, 2018
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Longstanding and equally lethal infectious disease crises have continued unabated in the background of the COVID-19 pandemic. While the 2020 mortality data is still being assessed, malaria, which kills more than 400,000 people ...
Nov 16, 2021
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