Studies of interactions between two lab-generated monoclonal antibodies (mAbs) and an essential Epstein-Barr virus (EBV) protein have uncovered targets that could be exploited in designing treatments and vaccines for this ...
Mar 12, 2024
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101
Listeria bacteria in food, water, or soil can cause food poisoning and even life-threatening infections in vulnerable people. In a study, Yale investigators have described how the pathogen manipulates the immune system to ...
Jun 27, 2019
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B cells and the antibodies they produce play an important role in our immune system, protecting us from the microscopic enemies that make us ill. Uncovering how they form and are "programmed" during development is key to ...
Oct 12, 2022
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The hygiene hypothesis may explain why asthma and other allergic airway diseases have dramatically increased over the past decades in industrialized countries. The hypothesis suggests that decreased exposure to microbial ...
Jan 9, 2019
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The flu and other viral infections have long been known to cause mood changes, beyond the more familiar symptoms of fever and sore throat. A study in mice, published April 19, 2016 in Immunity, now reveals how the antiviral ...
Apr 19, 2016
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VRAC/LRRC8 chloride channels not only play a decisive role in the transport of cytostatics, amino acids and neurotransmitters. They can also transport the important messenger substance cGAMP from cell to cell and thus strengthen ...
Apr 13, 2020
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A metabolic enzyme that has been studied in cancer biology and is important for T cell function may offer a new target for anti-inflammatory therapeutics, Vanderbilt researchers have discovered. They report Nov. 11 in the ...
Nov 11, 2021
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As warmer temperatures herald the arrival of pesky mosquitoes, researchers are feverishly working on several promising vaccines against Zika, a virus notorious for infecting humans through this insect's bite.
Mar 3, 2017
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A new study has identified how blocking a special set of molecules on the surface of T cells can suppress the heart's immune response – responsible for transplant rejection and autoimmune diseases such as myocarditis – ...
Jun 17, 2015
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Researchers at Karolinska Institutet in Sweden report that cholesterol metabolites cause specific immune cells in the large intestine to move, which lies behind the formation of the immune system's important lymphoid tissue ...
Jan 16, 2018
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