Journal of Biological Chemistry

Parkinson's & Movement disorders

Tracing the path of Parkinson's disease proteins

As neurodegenerative disorders such as Parkinson's and Alzheimer's disease progress, misfolded proteins clump together in neurons, recruiting normal proteins in the cell to also misfold and aggregate. Cells in which this ...

Diseases, Conditions, Syndromes

New study targets lethal fungal infection

The development of new drugs to fight a common fungal pathogen which kills half a million people globally each year is a step closer thanks to a University of Queensland-led study.

Neuroscience

Using omega 3 fatty acids to treat Alzheimer's, other diseases?

Understanding how dietary essential fatty acids work may lead to effective treatments for diseases and conditions such as stroke, Alzheimer's disease, age-related macular degeneration, Parkinson's disease and other retinal ...

Neuroscience

How one drug could affect pain, memory and nicotine addiction

Although pain, memory and nicotine addiction may not seem to be related, they actually share a common player: the nicotinic acetylcholine receptors. That's why Texas A&M researchers are working to develop drugs to enhance ...

Medical research

Complex mechanisms in Gaucher disease unravelled

Gaucher disease is a genetic disorder of lipid metabolism. Sphingosine, a compound as enigmatic as the sphinx, plays a key role in this metabolic disorder. Scientists from the Bonn research center caesar have identified some ...

Cardiology

Limiting protein reduces post-heart attack injury in mice

According to the Centers for Disease Control and Prevention, approximately 735,000 Americans experience a heart attack each year. Opening a blocked coronary artery to restore blood flow to the heart prevents sudden cardiac ...

Diabetes

Researchers implicate suspect in heart disease linked to diabetes

People with diabetes are at high risk of developing heart disease. Despite knowing this, scientists have struggled to trace the specific biology behind that risk or find ways to intervene. Now, UNC School of Medicine researchers ...

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