Journal of Controlled Release

Cancer

To fight lung cancer, researchers think small

In a study published in the Journal of Controlled Release, University of Kentucky Markey Cancer Center researchers used nanoparticles to deliver powerful chemotherapy drugs directly to lungs affected by metastatic disease ...

Cancer

Focused delivery for brain cancers

A person's brainstem controls some of the body's most important functions, including heart beat, respiration, blood pressure and swallowing. Tumor growth in this part of the brain is therefore twice as devastating. Not only ...

Cancer

Boron carrier for targeted tumour therapy

Scientists at Tokyo Institute of Technology have developed a boron carrier for use in targeted radiation treatment for cancerous tumours. The carrier is based on a common blood plasma protein, meaning it can be tailored to ...

Alzheimer's disease & dementia

The dawn of mRNA-based therapeutics for brain diseases

The progressive dementia suffered by patients with Alzheimer's disease (AD) affects millions of people globally each year and puts considerable strain on healthcare services. The mechanisms behind AD are not yet clear, and ...

Medical research

Regenerative bandage heals diabetic wounds faster

At some point in their lives, 15 percent of people with diabetes will develop a painful and hard-to-treat foot ulcer. Twenty-four percent of those affected will require a lower-leg amputation because of it. And, in some instances, ...

Diseases, Conditions, Syndromes

New method could deliver DNA-based vaccines in pill form

A microscopic corn-and-shrimp cocktail could eventually make DNA-based vaccinations and cancer-treating gene therapies an easier pill to swallow, according to new research from the University of Nebraska-Lincoln.

Cardiology

The vascular bypass revolution

Coronary or peripheral bypasses are the most frequently performed vascular operations. Although one million patients per year and around the world, undergo this intervention, its failure rate reaches 50%, because of poor ...

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