Molecular Cancer Therapeutics publishes the best science in the categories of Therapeutic Discovery, Preclinical Development, and Molecular Medicine in Practice. The journal provides a publication forum for these emerging disciplines that is focused specifically on cancer research. Papers are stringently reviewed and only those that report results of novel, timely, and significant research and meet high standards of scientific merit will be accepted for publication.
Combining a pair of experimental drugs may help treat malignant peripheral nerve sheath tumors with fewer harmful side effects, according to preliminary animal studies led by investigators at the Johns Hopkins Kimmel Cancer ...
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Cisplatin is widely used as a chemotherapeutic agent for the treatment of various solid tumors, including bladder, ovarian, and esophageal tumors. However, on metabolism by an enzyme called "cysteine conjugate beta-lyase ...
May 23, 2023
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Old medicines, combined in new ways, are showing promise for treating bowel cancer, a group of University of Auckland researchers has found.
Oct 12, 2022
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Glioblastoma multiforme (GBM) is one of the most aggressive, fast-growing tumor types, and the most common cancer of the brain with a median overall survival of approximately 15 months. Despite recent advances in treatment ...
Aug 2, 2022
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Chimeric antigen receptor T-cell therapy, or CAR T, has made a big impact on the treatment of certain blood cancers, allowing patients with relapsed/refractory disease to live longer, healthier lives. But in clinical study, ...
May 5, 2022
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Scientists have created a prototype test that can predict which drug combinations are likely to work for cancer patients in as little as 24 to 48 hours.
Apr 4, 2022
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A research team led by scientists at Roswell Park Comprehensive Cancer Center has discovered a molecule that inhibits the growth and metastasis of pancreatic cancer cells through the iron metabolism pathway. Their findings, ...
Mar 3, 2022
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A study by Virginia Commonwealth University Massey Cancer Center researchers published in today's print edition of Molecular Cancer Therapeutics shows that triplatin is effective against triple negative breast cancer, which ...
Feb 8, 2022
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Glioblastomas are the most common and most aggressive brain tumors. Their survival rate has barely increased over the last 50 years, indicating an urgent need to develop new therapeutic strategies. In a paper published this ...
Apr 12, 2021
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Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified a drug candidate that blocks the uptake of glutamine, a key food source for many tumors, and slows the growth of melanoma. The drug is a small ...
Mar 19, 2021
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