Nature Biotechnology

Genetics

Experimental therapy may offer hope for rare genetic disorders

Researchers at Massachusetts General Hospital (MGH) have developed a new way to alleviate problems caused by dysfunctional mitochondria, which are the "powerhouses" that produce energy in cells. Their discovery, reported ...

Medical research

A 'super-cool' method for improving donated liver preservation

A new method for super-cooling human donor livers to subzero centigrade temperatures without freezing can triple the time that a donor organ stays safe and viable during transportation from the donor to the recipient. This ...

Neuroscience

The future of mind control

Electrodes implanted in the brain help alleviate symptoms like the intrusive tremors associated with Parkinson's disease. But current probes face limitations due to their size and inflexibility. "The brain is squishy and ...

Medical research

New clues on stem cell transplant rejection revealed in study

In 2006, scientists discovered a way to "reprogram" mature cells—adult skin cells, for example—into stem cells that could, in principle, give rise to any tissue or organ in the body. Many assumed it was only a matter ...

Cardiology

New stem cell combination could help to repair damaged hearts

A combination of heart cells derived from human stem cells could be the answer to developing a desperately-needed treatment for heart failure, according to new research part-funded by the British Heart Foundation (BHF) and ...

Oncology & Cancer

Immune therapy takes a 'BiTE' out of brain cancer

Building on their research showing that an exciting new form of immunotherapy for cancer has activity in patients with glioblastoma, the most common and most deadly form of brain cancer, Massachusetts General Hospital (MGH) ...

Oncology & Cancer

The declining impact of federal funding on cancer innovation

Cancer research is a field that has been especially dependent on public funding. The National Cancer Institute (NCI), an independent institute of the National Institutes of Health (NIH), was established in 1937 to provide ...

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