Insufficient oxygen to an area like the heart or legs, called hypoxia, is a cue to our bodies to make more blood vessels, and scientists have found some unusual partners are key to making that happen.
Mar 8, 2022
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27
Researchers at the University of North Carolina at Chapel Hill and the UNC Lineberger Comprehensive Cancer Center have uncovered a new role of a chromatin-modulatory enzyme, termed EZH2, during cancer development. They then ...
Feb 24, 2022
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120
Scientists have revealed how cancer can resist PARP inhibitors, a precision medicine used to treat thousands of patients worldwide.
Jan 11, 2022
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64
Severe injuries to the lung from diseases such as COVID-19 trigger abnormal stem cell repair that alters the architecture of the lung. The aberrant stem cell differentiation in response to injury can prevent the restoration ...
Dec 30, 2021
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317
Researchers have succeeded in establishing a mouse model that develops gastric cancer closely resembling advanced human gastric cancer. Using this model, they have discovered gastric cancer stem cells, i.e. Lgr5+ gastric ...
Dec 22, 2021
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66
Researchers at Vanderbilt University Medical Center have discovered a nanoparticle released from cells, called a "supermere," which contains enzymes, proteins and RNA associated with multiple cancers, cardiovascular disease, ...
Dec 13, 2021
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334
A research group at the University of Turku, Finland, has discovered a completely new mechanism that cells use to circulate integrins on the cell surface. Aggressive breast cancer cells exploit this mechanism to spread and ...
Oct 18, 2021
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Researchers at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) have generated the first "atlas" of human melanocytes located throughout the body. In analyzing the atlas data further, the researchers discovered ...
Sep 3, 2021
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61
Why people suffer from chronic inflammatory bowel diseases (IBD) such as ulcerative colitis is only partially understood. However, it is known that the bacteria of the intestinal flora and dysfunction in the immune system ...
Aug 12, 2021
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613
Chemotherapy is widely used to treat cancer patients. During the treatment, chemotherapeutic agents affect various biochemical processes to kill or reduce the growth of cancer cells, which divide uncontrollably in patients. ...
Jul 12, 2021
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