Nature Genetics

Oncology & Cancer

Possible origin of neuroblastoma in the adrenal glands discovered

Neuroblastoma is a childhood cancer, most commonly affecting children aged between two to three and can be fatal. Since the tumor cells resemble certain cells in the adrenal glands, a joint research group from MedUni Vienna's ...

Oncology & Cancer

Mitochondrial DNA in cancer: Small genome, big impact

Mitochondria are in vogue, with devotees ranging from exercise physiologists and sports scientists to molecular biologists and clinicians all coalescing around these unusual organelles.

Oncology & Cancer

Pediatric cancers have unique genetic vulnerabilities

Most cancer drugs that target specific genetic mutations are designed for adult cancers rather than those in children, partly because pediatric cancers have fewer mutations. To look for more ways to target childhood cancers, ...

Genetics

Induced pluripotent stem cells reveal causes of disease

Induced pluripotent stem cells (iPSC) are suitable for discovering the genes that underly complex, rare genetic diseases. Scientists from the German Cancer Research Center (DKFZ) and the European Molecular Biology Laboratory ...

Oncology & Cancer

Why some melanoma patients do not respond to immunotherapy

By harnessing the immune system against cancer, immunotherapies have revolutionized the way some types of cancer are treated. But most patients—across cancer types—do not respond, and in most cases, scientists are at ...

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