Each gene in the human genome has two copies. When researchers detect two mutations within a particular gene in a patient's genome, it can be difficult or expensive to determine if those two mutations are present in the same ...
Dec 7, 2023
0
62
A Yale-led analysis of the genomes of more than 1 million people has shed light on the underlying biology of cannabis use disorder and its links to psychiatric disorders, abuse of other substances such as tobacco, and possibly ...
Nov 21, 2023
0
49
Understanding how the human pancreas develops is crucial to allow scientists to make insulin producing–beta cells in the quest to cure type 1 diabetes. Now, scientists have made a unique and surprising discovery—a gene ...
Nov 16, 2023
0
37
A study of newly created databases of medulloblastoma has found that patients with tumors containing circular extrachromosomal DNA—loops of DNA found outside of regular chromosomes—are twice as likely to relapse and three ...
Nov 14, 2023
0
18
Researchers at Duke University have adapted CRISPR technologies for high-throughput screening of gene function in human immune cells and discovered that a single master regulator of the genome can be used to reprogram a network ...
Nov 9, 2023
0
60
A globe-spanning scientific team has compiled the most comprehensive list of genetic variants associated with prostate cancer risk—451 in all—through a whole-genome analysis that ranks as the largest and most diverse ...
Nov 9, 2023
0
51
A comprehensive new study from deCODE genetics published in Nature Genetics, provides insights into the epidemiology and somatic and germline genetics of clonal hematopoiesis. Whole genome sequence data from Iceland and the ...
Nov 6, 2023
0
20
As people age, the DNA in their cells begins to accumulate genetic mutations. Mosaic chromosomal alterations (mCAs), a category of mutations acquired in blood cells, are linked with a 10-fold increased risk of developing ...
Nov 1, 2023
0
26
RIKEN geneticists have developed a tool that can quickly and accurately analyze variants in mobile genetic elements, commonly known as "jumping genes." This promises to shed light on the role such variants play in disease.
Oct 31, 2023
0
39
Psoriasis—a chronic skin condition—is not caused or spread by spontaneous genetic mutations in the skin, new research suggests.
Oct 26, 2023
0
86
