Nature Reviews Drug Discovery is a review journal with an emphasis on drug discovery and development. With an impact factor of 28.712 in 2010 it is the leading journal in pharmacology/pharmacy and biotechnology/applied microbiology areas. The reviews are commissioned to leaders in the their specialties (non-commissioned review submissions are discouraged), but are also peer-reviewed after submission. The reviews are supplemented with glossary explanations for non-specialist readers and illustrated with figures drawn by Nature's in-house art editors. Besides reviews, the journal accepts peer-reviewed analysis articles based on existing datasets (e.g. metaanalysis), progress articles that focus on outstanding issues, and perspective articles—typically opinions or historical pieces.
Autoinflammatory syndromes are often the result of genetic mutations that ultimately compromise neutrophils, macrophages and other cells of the innate immune system. Rather than showering sufferers with broad immunosuppressives, ...
A team of researchers in biomedical engineering, mechanical engineering and biomechanics in Ireland, the Netherlands and the U.S. recently developed 3-D bioprinted implants optimized with growth factors to facilitate angiogenesis—blood ...
You awake in the middle of the night from a nightmare.
Feb 10, 2020
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NASCAR has nothing on cancer cells when it comes to exploiting the power of drafting, letting someone else do the hard work of moving forward while you coast behind.
Mar 25, 2019
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A diagnosis of Alzheimer's disease is devastating for those affected, as there is still no cure for this type of dementia. One hundred years after Alois Alzheimer first described it, we neither have a drug for it, nor do ...
Jun 1, 2018
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Major depressive disorder (MDD) impacts 15 million Americans and is the leading cause of disability, yet current treatments possess limited efficacy. Ketamine, which has been repurposed as a rapidly acting antidepressant, ...
Mar 17, 2017
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Without a steady supply of blood, neurons can't work. That's why one of the culprits behind Alzheimer's disease is believed to be the persistent blood clots that often form in the brains of Alzheimer's patients, contributing ...
Jun 28, 2014
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Scientists have created a map of all 1,578 licensed drugs and their mechanisms of action - as a means of identifying 'uncharted waters' in the search for future treatments.
Dec 5, 2016
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Some diseases are like black swans. They occur so rarely that many physicians never encounter them in their clinical practice, complicating efforts to treat them.
Feb 4, 2020
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Literal heartbreak, from illness or injury, triggers the body's natural healing mechanisms. The result of such mending is often a scar. It's a patch that works, but fibrotic scar tissue replaces healthy heart muscle, a problem ...
Jun 27, 2016
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