Nature Reviews Drug Discovery

Medical research

Drug screens and CRISPR combine to help make better cancer drugs

A new study has created the most comprehensive analysis for understanding how cancer drugs work at a molecular level. Scientists at the Wellcome Sanger Institute, EMBL's European Bioinformatics Institute (EMBL-EBI) and AstraZeneca ...

Medications

Scientists suggest new solution to the rare-disease problem

Thousands of rare diseases cumulatively affect millions of people across the globe, yet because each case is so rare doctors struggle to accurately diagnose and effectively treat individual patients. Every time a patient ...

Medications

New research predicts market share for drug makers

Lagging behind in launching new medicines means a much smaller market share for pharmaceutical companies—even if they spend just as much on advertising, according to new research from Duke University's Fuqua School of Business.

Medications

Culmination of project to share data on the safety of medicines

eTRANSAFE, the European project to share data on the safety of medicines, has come to fruition. On a single platform, the project has integrated data from more than 10,000 pharmacological studies by reference pharmaceutical ...

Neuroscience

How to improve multiple sclerosis therapy

Medications currently used to treat multiple sclerosis (MS) can merely reduce relapses during the initial relapsing-remitting phase. Many patients, however, develop progressive MS at a later stage, with disability becoming ...

Medications

Drug research and development more efficient than expected

Drug R&D costs have increased substantially in recent decades, while the number of new drugs has remained fairly constant, leading to concerns about the sustainability of drug R&D and question about the factors that could ...

Medications

Characteristics of international drug regulatory regimes

The regulatory requirements for the approval of new drugs vary greatly internationally in regards to the resources allocated to the authorities, the evaluation periods for approval and the fees for the pharmaceutical companies. ...

Medications

Study finds benefit to rapid drug licensing

(Medical Xpress)—Paying too much heed to possible risks when licensing a medication can lead to a pharmaceutical of great benefit to patients either not being licensed or else having its use restricted. For this reason, ...

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