Study: Theta rhythm reduces seizure rate

Texas scientists say the brain's septum helps stop epileptic seizures by inducing electrical activity in another area of the brain called the hippocampus.

Researchers at the University of Texas-Brownsville found that imposing a normal "theta" rhythm on epileptic rats reduced the rate of seizures by 86 percent to 97 percent.

The septum acts as a conductor, orchestrating brain impulses as they pass from the brain stem through the septum and on to the hippocampus, said the study's lead researcher, Luis Colom. The hippocampus is a part of the brain that plays a role in memory, spatial navigation and sensory motor integration, among other functions.

"My hypothesis is that the septum keeps the electrical activity of neurons within certain areas of the brain working within normal ranges," Colom said. "By keeping the neurons firing normally, the septum inhibits neuronal hyperexcitability, such as epilepsy, and hypoexcitablity, such as Alzheimer's disease." In addition, he said, septal impulses may help to maintain the anatomical integrity of other brain structures.

The research appears in the June issue of the Journal of Neurophysiology.

Copyright 2006 by United Press International


Explore further

Scientists reveal complexity in the brain's wiring diagram

Citation: Study: Theta rhythm reduces seizure rate (2006, June 20) retrieved 24 October 2020 from https://medicalxpress.com/news/2006-06-theta-rhythm-seizure.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
 shares

Feedback to editors

User comments