High blood pressure, high cholesterol may be associated with retinal vascular disease

May 12, 2008

High blood pressure and high cholesterol levels appear to be risk factors for retinal vein occlusion, a condition that causes vision loss, according to a report in the May issue of Archives of Ophthalmology.

Retinal vein occlusion occurs when one or more veins carrying blood from the eye to the heart become blocked, according to background information in the article. Bleeding (hemorrhage) or fluid buildup (edema) may follow, damaging vision.

Paul R.A. O’Mahoney, of the Royal College of Surgeons in Ireland, Dublin, and colleagues conducted a meta-analysis of 21 previously published studies involving 2,916 individuals with retinal vein occlusion and 28,646 control participants without the condition. The researchers pooled data from all the studies and estimated the population-attributable risk, or the percentage of cases of retinal vein occlusion that could be attributed to hypertension (high blood pressure), diabetes and hyperlipidemia (high cholesterol).

Of patients with retinal vein occlusion, 63.6 percent had hypertension, compared with 36.2 percent of controls; those with high blood pressure had more than 3.5 times the odds of having retinal vein occlusion. High cholesterol levels were more than twice as common among patients with retinal vein occlusion as those without (35.1 percent vs. 16.7 percent), and those with high cholesterol levels had an approximately 2.5-fold higher risk of retinal vein occlusion. Diabetes was slightly more prevalent among those with retinal vein occlusion than among those without (14.6 percent vs. 11.1 percent).

“The pronounced population attributable risk percentage for hypertension (nearly 50 percent), hyperlipidemia (20 percent) and diabetes mellitus (5 percent) in persons with retinal vein occlusion, if causal, would mean that treatment of these diseases might be important in the primary and secondary prevention of retinal vein occlusion,” the authors write. “Accordingly, we recommend that an assessment of blood pressure and both fasting lipid and glucose levels be routinely performed in adults with any form of retinal vein occlusion.”

Source: JAMA and Archives Journals

Explore further: Surgical eye robot performs precision injection in patient with retinal vein occlusion

Related Stories

Surgical eye robot performs precision injection in patient with retinal vein occlusion

January 26, 2017
Eye surgeons at University Hospitals Leuven have been the first to use a surgical robot to operate on a patient with retinal vein occlusion. The robot uses a needle of barely 0.03 millimetre to inject a thrombolytic drug ...

Avastin as effective as Eylea for treating central retinal vein occlusion

May 9, 2017
Monthly eye injections of Avastin (bevacizumab) are as effective as the more expensive drug Eylea (aflibercept) for the treatment of central retinal vein occlusion (CRVO), according to a clinical trial funded by the National ...

Central retinal vein occlusion ID'd after phendimetrazine use

February 8, 2016
(HealthDay)—A case of central retinal vein occlusion (CRVO) two days after phendimetrazine use has been documented and published online Feb. 4 in JAMA Ophthalmology.

Young scientist helps identify cause of widespread eye disease

December 21, 2012
Branch retinal vein occlusion – blockage of the blood vessels that channel blood from the retina – is a common eye disease. A type of blood clot in the eye, the disease causes reduced vision, and people with the disease ...

Aflibercept in macular oedema after BRVO: No hint of added benefit

June 23, 2015
Since February 2015, aflibercept (trade name Eylea) has been available also for patients with impaired vision due to macular oedema that follows blockage of branch veins of the central retinal vein (branch retinal vein occlusion, ...

Changes of the cell environment are associated with certain eye diseases

March 15, 2017
Ischemic disorders of the retina are a frequent cause of blindness. The surrounding cellular protein scaffold might play a crucial role in this process.

Recommended for you

Pneumonia vaccine under development provides 'most comprehensive coverage' to date, alleviates antimicrobial concerns

October 20, 2017
In 2004, pneumonia killed more than 2 million children worldwide, according to the World Health Organization. By 2015, the number was less than 1 million.

Newly discovered viral marker could help predict flu severity in infected patients

October 20, 2017
Flu viruses contain defective genetic material that may activate the immune system in infected patients, and new research published in PLOS Pathogens suggests that lower levels of these molecules could increase flu severity.

H7N9 influenza is both lethal and transmissible in animal model for flu

October 19, 2017
In 2013, an influenza virus that had never before been detected began circulating among poultry in China. It caused several waves of human infection and in late 2016, the number of people to become sick from the H7N9 virus ...

Flu simulations suggest pandemics more likely in spring, early summer

October 19, 2017
New statistical simulations suggest that Northern Hemisphere flu pandemics are most likely to emerge in late spring or early summer at the tail end of the normal flu season, according to a new study published in PLOS Computational ...

New insights into herpes virus could inform vaccine development

October 18, 2017
A team of scientists has discovered new insights into the mechanisms of Epstein-Barr virus (EBV) infection, as well as two antibodies that block the virus' entry into cells. The findings, published in Proceedings of the National ...

Pair of discoveries illuminate new paths to flu and anthrax treatments

October 17, 2017
Two recent studies led by biologists at the University of California San Diego have set the research groundwork for new avenues to treat influenza and anthrax poisoning.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.