Immunological study finds earlier way to diagnose axon and neuron degeneration in MS

July 30, 2010

UCI immunologists have found that testing for increased levels of antibodies that inhibit energy production in neurons can detect axon and neuron degeneration in multiple sclerosis earlier than existing diagnostic tools.

The study, led by Yufen Qin, assistant professor of neurology, shows how these inhibitors trigger degeneration of axons and neurons, which results in demyelination, or the breakdown of neurons' protective coating.

Current spinal fluid tests for MS focus on demyelination, she says.

Qin adds that measuring these , which inhibit an enzyme called GAPDH, could lead to earlier and more effective long-term treatment for MS - a chronic, often disabling disease that attacks the .

The study appears online in The Journal of Immunology.

Related Stories

Recommended for you

Survivors of childhood brain tumors have increased body fat

March 24, 2017

McMaster University researchers have discovered that while survivors of childhood brain tumours have a similar Body Mass Index (BMI) to healthy children with no cancer, they have more fat tissue overall, and especially around ...

Scientists unveil a giant leap for anti-aging

March 23, 2017

UNSW researchers have made a discovery that could lead to a revolutionary drug that actually reverses ageing, improves DNA repair and could even help NASA get its astronauts to Mars.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.