Recent improvement in 3D ECHO accuracy for LV mass

May 3, 2012
Recent improvement in 3D ECHO accuracy for LV mass
In the past decade there has been an improvement in the accuracy of three-dimensional echocardiography for measurement of left ventricular mass, according to a meta-analysis published online April 30 in The American Journal of Cardiology.

(HealthDay) -- In the past decade there has been an improvement in the accuracy of three-dimensional echocardiography (3DE) for measurement of left ventricular (LV) mass, according to a meta-analysis published online April 30 in The American Journal of Cardiology.

Yuichi J. Shimada, M.D., of the Beth Israel Medical Center in New York City, and Takahiro Shiota, M.D., Ph.D., of the University of California in Los Angeles, conducted a literature review and meta-analysis to investigate the accuracy of 3DE for measurement of LV mass, and the change in accuracy over time.

The researchers identified 25 studies, which included 671 comparisons. High heterogeneity was seen in studies published in or before 2004 (I² = 69 percent), with a significant underestimation of LV mass (−5.7 g; P = 0.04). was still seen in studies published from 2005 to 2007 (I² = 60 percent) but there was less systematic bias (− 0.5 g; P = 0.63). Studies published in or after 2008 were very homogenous (I² = 3 percent) and highly accurate (−0.1 g; P = 0.90). The comparison of cardiac patients with healthy volunteers led to a significantly larger bias.

"This meta-analysis elucidates the underestimation of LV mass by 3DE, its improvement over the past decade, and factors affecting the bias," the authors write. "These data provide a more detailed basis for improving the accuracy of 3DE, an indispensable step toward further clinical application."

Explore further: EAE/ASE 3D echocardiography image acquisition recommendations

More information: doi:10.1016/j.amjcard.2012.03.046

Related Stories

EAE/ASE 3D echocardiography image acquisition recommendations

January 3, 2012
For the first time, a joint committee of the European Association for Echocardiography and the American Society of Echocardiography have issued recommendations on image acquisition using three-dimensional echocardiography ...

Study examines outcomes of erythropoietin use for heart attack patients undergoing PCI

May 10, 2011
Intravenous administration of epoetin alfa, a product that stimulates red blood cell production, to patients with heart attack who were undergoing percutaneous coronary intervention (PCI; procedures such as balloon angioplasty ...

Study examines treatment of heart failure with bone marrow cells

March 24, 2012
Use of a patient's bone marrow cells for treating chronic ischemic heart failure did not result in improvement on most measures of heart function, according to a study appearing in JAMA. The study is being published early ...

Study examines link between blood biomarkers and risk of Alzheimer's disease

March 26, 2012
A meta-analysis of previously published studies found that the ratio of blood plasma amyloid-β (Aβ) peptides Aβ42:Aβ40 was significantly associated with development of Alzheimer disease and dementia, according ...

Low amounts of alcohol have different effects on left and right ventricles of the heart

July 15, 2011
Few studies have examined the acute effects of alcohol on myocardial or heart function. While moderate-to-high blood concentrations of alcohol acutely impair conventional echocardiographic measures of left ventricular (LV) ...

Long-term cardiac effects for childhood cancer survivors

March 7, 2012
(HealthDay) -- Regardless of exposure to cardiotoxic cancer therapies, survivors of childhood cancers display cardiovascular abnormalities and have markers of increased systemic inflammation and atherosclerotic disease, according ...

Recommended for you

Five vascular diseases linked to one common genetic variant

July 27, 2017
Genome-wide association studies have implicated a common genetic variant in chromosome 6p24 in coronary artery disease, as well as four other vascular diseases: migraine headache, cervical artery dissection, fibromuscular ...

Could aggressive blood pressure treatments lead to kidney damage?

July 18, 2017
Aggressive combination treatments for high blood pressure that are intended to protect the kidneys may actually be damaging the organs, new research from the University of Virginia School of Medicine suggests.

Quantifying effectiveness of treatment for irregular heartbeat

July 17, 2017
In a small proof-of-concept study, researchers at Johns Hopkins report a complex mathematical method to measure electrical communications within the heart can successfully predict the effectiveness of catheter ablation, the ...

Concerns over side effects of statins stopping stroke survivors taking medication

July 17, 2017
Negative media coverage of the side effects associated with taking statins, and patients' own experiences of taking the drugs, are among the reasons cited by stroke survivors and their carers for stopping taking potentially ...

Study discovers anticoagulant drugs are being prescribed against safety advice

July 17, 2017
A study by researchers at the University of Birmingham has shown that GPs are prescribing anticoagulants to patients with an irregular heartbeat against official safety advice.

Protein may protect against heart attack

July 14, 2017
DDK3 could be used as a new therapy to stop the build-up of fatty material inside the arteries

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.