Sleep apnea severity linked to glycated hemoglobin levels

June 18, 2012
Sleep apnea severity linked to glycated hemoglobin levels
For adults without diabetes, obstructive sleep apnea severity is independently associated with impaired glucose metabolism, as measured by glycated hemoglobin levels, according to a study published online June 11 in Diabetes Care.

(HealthDay) -- For adults without diabetes, obstructive sleep apnea (OSA) severity is independently associated with impaired glucose metabolism, as measured by glycated hemoglobin (HbA1c) levels, according to a study published online June 11 in Diabetes Care.

Pascaline Priou, M.D., of LUNAM University in Angers, France, and colleagues conducted a large cross-sectional study involving 1,599 patients with OSA. HbA1c levels were measured, and patients with diabetes, use of , or HbA1c levels ≥6.5 percent were excluded.

The researchers found that increased with increasing OSA severity, as measured by the apnea-hypopnea index (AHI), with the percent of patients with HbA1c increasing from 10.8 to 34.2 percent for those with AHI values <5 to ≥50, respectively. After adjusting for potential confounding factors, the odds ratios of a patient having an HbA1c level >6.0 percent increased from 1.0 (reference) for AHI <5; to 1.40 for AHI of ≥5 to <15; to 1.8 for AHI of ≥15 to <30; to 2.02 for AHI of ≥30 to <50; to 2.96 for AHI of ≥50. Additionally, an independent association was found between increasing hypoxemia during sleep and the odds of an elevated HbA1c level.

"Among adults without known diabetes, increasing OSA severity is independently associated with impaired , as assessed by higher HbA1c values, which may expose them to higher risks of diabetes and cardiovascular disease," the authors write.

Explore further: Severity of sleep disordered breathing predicts glycemic health

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Severity of sleep disordered breathing predicts glycemic health

May 23, 2012
The severity of sleep disordered breathing and nocturnal hypoxemia independently predict both glycosylated hemoglobin (HbA1c) levels and type 2 diabetes mellitus (T2DM), according to a new study.

Obstructive sleep apnea is associated with diabetic peripheral neuropathy

June 15, 2012
Obstructive sleep apnea (OSA) is independently associated with diabetic peripheral neuropathy (DPN) in patients with type 2 diabetes mellitus (T2DM), according to a new study from researchers in the UK. The severity of DPN ...

Isomaltulose doesn't improve glycemic control in diabetes

April 13, 2012
(HealthDay) -- For patients with type 2 diabetes, substitution of sucrose with isomaltulose is not associated with improved glycemic control (measured by hemoglobin A1c [HbA1c] levels) at 12 weeks, according to a study published ...

Study assesses glucose monitoring trends in tweens

April 12, 2012
(HealthDay) -- During the transition to adolescence, children with type 1 diabetes monitor their blood glucose less frequently, resulting in significant increases in HbA1c levels, according to research published online April ...

Structured exercise training associated with improved glycemic control for patients with diabetes

May 3, 2011
Implementing structured exercise training, including aerobic, resistance or both, was associated with a greater reduction in hemoglobin A1c levels (a marker of glucose control) for patients with diabetes compared to patients ...

Recommended for you

Anti-nausea drug could help treat sleep apnea

June 6, 2017
An old pharmaceutical product may be a new treatment for obstructive sleep apnea, according to new research presented today by University of Illinois at Chicago and Northwestern University scientists at the SLEEP 2017 annual ...

New disposable, wearable patch found to effectively detect sleep apnea

June 4, 2017
Results of a definitive clinical trial show that a new, disposable diagnostic patch effectively detects obstructive sleep apnea across all severity levels.

Childhood sleep apnoea is common but hard to diagnose

April 28, 2017
The cessation of breathing during sleep caused by enlarged tonsils is common in preschool-age children and can cause serious complications, but the methods normally used to diagnose the condition are subjective and unreliable. ...

Curbing sleep apnea might mean fewer night trips to bathroom

March 27, 2017
(HealthDay)—Millions of Americans battle bothersome nighttime conditions, such as sleep apnea or the need to get up frequently to urinate.

Untreated sleep apnea in children can harm brain cells tied to cognition and mood

March 17, 2017
A study comparing children between 7 and 11 years of age who have moderate or severe obstructive sleep apnea to children the same age who slept normally, found significant reductions of gray matter - brain cells involved ...

Dietary supplement derived from tree bark shows promise for treating obstructive sleep apnea

February 24, 2017
Obstructive sleep apnea, which causes people to briefly stop breathing while asleep, affects an estimated 5 percent of the population, not including the many more who don't even realize they suffer from the disorder.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.