Childhood famine increases risk of type 2 diabetes

June 5, 2012
Childhood famine increases risk of type 2 diabetes
Even a short period of moderate or severe undernutrition or famine during childhood or adolescence can increase the risk of developing type 2 diabetes in adulthood, according to research published online May 29 in Diabetes.

(HealthDay) -- Even a short period of moderate or severe undernutrition or famine during childhood or adolescence can increase the risk of developing type 2 diabetes in adulthood, according to research published online May 29 in Diabetes.

Annet F.M. van Abeelen, Ph.D., of the University Medical Center Utrecht in the Netherlands, and colleagues conducted a study involving 7,837 women from the European Prospective Investigation Into Cancer and Nutrition study who had been exposed to the 1944 to 1945 Dutch famine between the ages of 0 to 21 years. The association between during childhood and adolescence with type 2 diabetes in adulthood was explored.

After adjusting for potential confounders, including age at famine exposure, smoking, and , the researchers found that there was a dose-response association between self-reported famine exposure and the risk of type 2 diabetes. Relative to unexposed women, those who were exposed to moderate famine had an age-adjusted hazard ratio of 1.36 for type 2 diabetes, and those exposed to severe famine had an age-adjusted hazard ratio of 1.64. The associations persisted after adjustment for confounding variables.

"This study demonstrates for the first time, by using individual famine exposure data, that a short period of severe undernutrition during childhood or young adolescence is associated with an increased risk of in , in a dose-dependent manner," the authors write.

Explore further: Undernutrition in childhood, adolescence or young adulthood increases risk of heart disease later

More information: Abstract
Full Text (subscription or payment may be required)


Related Stories

Undernutrition in childhood, adolescence or young adulthood increases risk of heart disease later

August 25, 2011
A study of women who were children, teenagers or young adults during the Dutch famine in 1944-45 has shown that undernutrition, particularly in the adolescent years, is associated with an increased risk of coronary heart ...

In Taiwan, diabetes linked to increased Parkinson's risk

April 2, 2012
(HealthDay) -- Individuals with diabetes in Taiwan have a significantly increased risk of Parkinson's disease (PD), which is robust across most age and gender stratifications, according to a study published online March 19 ...

Diabetes linked to lung cancer in postmenopausal women

May 30, 2012
(HealthDay) -- Postmenopausal women with diabetes are at a significantly higher risk of developing lung cancer, particularly if they require insulin therapy, according to research published online May 22 in Diabetes Care.

Abused girls may have higher risk of heart disease, stroke as adults

November 13, 2011
Sexually and physically abused girls may have higher risks for heart attacks, heart disease and strokes as adults, according to research presented at the American Heart Association's Scientific Sessions 2011.

Recommended for you

Pancreatic islets study may spur diabetes treatment advances

September 22, 2017
Investigators in the Vanderbilt Diabetes Research and Training Center (VDRTC) and collaborators at Stanford University have discovered new insights into the molecular mechanisms of cell proliferation in juvenile human pancreatic ...

Finding a natural defense against clogged arteries

September 20, 2017
In type 2 diabetes, chronic inflammation drives cardiovascular disease, the leading cause of death among people with the condition. Researchers at Joslin Diabetes Center now have identified an unexpected natural protective ...

Study identifies blood vessel as a therapeutic target for diabetes

September 14, 2017
Blood vessels have an often overlooked role of regulating the transfer of nutrients from the blood to organs in the body. In a new Yale-led study, researchers have identified a role of a secreted protein, apelin, in regulating ...

Drug for type 2 diabetes provides significant benefits to type 1 diabetic patients

September 14, 2017
A majority of patients with Type 1 diabetes who were treated with dapagliflozin, a Type 2 diabetes medicine, had a significant decline in their blood sugar levels, according to a new study published in The Lancet Diabetes ...

Epigenetic 'fingerprint' identifies diabetes risk

September 14, 2017
Deakin researchers have identified an epigenetic marker that predicts risk of type 2 diabetes in women with gestational diabetes.

Could swine flu be linked to type 1 diabetes?

September 14, 2017
(HealthDay)—Young people who've been infected with the H1N1 swine flu virus may be at increased risk for type 1 diabetes, a new study suggests.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.