Hyperinsulinemia in early adulthood tied to later HTN

June 28, 2012
Hyperinsulinemia in early adulthood tied to later HTN
Young adults with hyperinsulinemia are significantly more likely to have hypertension later in life, regardless of sex, ethnicity, or body weight, according to a study published in the July issue of Diabetes Care.

(HealthDay) -- Young adults with hyperinsulinemia are significantly more likely to have hypertension (HTN) later in life, regardless of sex, ethnicity, or body weight, according to a study published in the July issue of Diabetes Care.

To determine the relationship between fasting insulin level and HTN, Pengcheng Xun, M.D., Ph.D., of the University of North Carolina at Chapel Hill, and colleagues conducted a prospective study involving 3,413 Americans aged 18 to 30 years without hypertension. Both radioimmunoassay and hexokinase methods were used to measure fasting insulin and .

During 20 years of follow-up, the researchers identified 796 incident cases of HTN. Compared with those in the lowest quartile, participants in the highest quartile of fasting had a significantly increased incidence (hazard ratio, 1.85). This association remained when comparing men and women, African-American and Caucasian ethnicities, and for individuals with different body weights.

"Fasting serum insulin levels or hyperinsulinemia in was positively associated with incidence of HTN later in life for both men and women, African-Americans and Caucasians, and those with normal weight and overweight," the authors write. "Our findings suggested that fasting insulin ascertainment may help clinicians identify those at high risk of HTN."

Explore further: ENDO: serum phthalate levels higher in obese children

More information: Abstract
Full Text (subscription or payment may be required)


Related Stories

ENDO: serum phthalate levels higher in obese children

June 25, 2012
(HealthDay) -- Serum levels of di(2-ethylhexyl) phthalate (DEHP) are increased in obese versus nonobese children, according to a study presented at the annual meeting of The Endocrine Society, held from June 23 to 26 in Houston.

Amino acid levels linked to type 2 diabetes risk

May 9, 2012
(HealthDay) -- Levels of some amino acids are associated with glycemia and insulin resistance and predict the development of type 2 diabetes in men, according to a study published online May 2 in Diabetes.

Recommended for you

Study identifies blood vessel as a therapeutic target for diabetes

September 14, 2017
Blood vessels have an often overlooked role of regulating the transfer of nutrients from the blood to organs in the body. In a new Yale-led study, researchers have identified a role of a secreted protein, apelin, in regulating ...

Drug for type 2 diabetes provides significant benefits to type 1 diabetic patients

September 14, 2017
A majority of patients with Type 1 diabetes who were treated with dapagliflozin, a Type 2 diabetes medicine, had a significant decline in their blood sugar levels, according to a new study published in The Lancet Diabetes ...

Could swine flu be linked to type 1 diabetes?

September 14, 2017
(HealthDay)—Young people who've been infected with the H1N1 swine flu virus may be at increased risk for type 1 diabetes, a new study suggests.

Epigenetic 'fingerprint' identifies diabetes risk

September 14, 2017
Deakin researchers have identified an epigenetic marker that predicts risk of type 2 diabetes in women with gestational diabetes.

Time to dial back on diabetes treatment in older patients? Study finds 11 percent are overtreated

September 14, 2017
Anyone with diabetes who takes blood sugar medication knows their doctor prescribed it to help them. After all, the long-term effects of elevated blood sugar can harm everything from the heart and kidneys to the eyes and ...

Novel way to present pancreatic proteins increases the sensitivity of type 1 diabetes tests

September 13, 2017
Researchers from the Johns Hopkins University School of Medicine, Stanford University and the University of Florida report the development of a novel antibody detection technology that holds promise for improving the accuracy ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.