PCI has excellent outcomes for younger adults with coronary artery disease

June 6, 2012
PCI has excellent outcomes for younger adults with CAD

(HealthDay) -- For younger adults with premature coronary artery disease (CAD), percutaneous coronary intervention (PCI) is associated with excellent short- and long-term outcomes, according to a study published in the June 15 issue of The American Journal of Cardiology.

Emanuele Meliga, M.D., Ph.D., of the Mauriziano Hospital in Turin, Italy, and colleagues conducted a retrospective study involving 214 consecutive patients, 40 years of age or younger, who underwent PCI for premature CAD with a bare-metal or drug-eluting stent. The immediate and long-term clinical outcomes were assessed.

The researchers found that a total of 272 stents were implanted, including 154 bare-metal stents and 118 drug-eluting stents. No patients died in the hospital, and the incidence of major cardiac and cerebrovascular events was 2.3 percent. After a median of 757 days of follow-up, 0.9 percent of patients had died and 12.6 percent required a new revascularization procedure. At the median follow-up point and at 1,818 days, the major adverse cardiac and cerebrovascular event-free survival rates were 89.6 and 84.2 percent, respectively. Independent predictors of events included active smoking and having a under 50 percent.

"In conclusion, PCI in young patients [leads] to excellent results in short- and long-term follow-up and should be considered as the treatment of choice," the authors write. "Traditional risk factors are important prognostic determinants of adverse events and might help identify higher-risk patients within this cohort."

Explore further: Long-term outcome similar with thrombus aspiration and stents in PCI

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Long-term outcome similar with thrombus aspiration and stents in PCI

May 2, 2012
New research confirms thrombus aspiration (TA) during percutaneous coronary intervention (PCI) in patients with acute ST-segment elevation myocardial infarction (STEMI) provides long-term outcomes similar to conventional ...

Positive results for unprotected left main coronary artery PCI with drug-eluting stents

June 22, 2011
Patients with normal left ventricular function who undergo elective unprotected left main coronary artery (ULMCA) percutaneous coronary intervention (PCI) with drug-eluting stents (DES) had favorable outcomes according to ...

Recommended for you

Could aggressive blood pressure treatments lead to kidney damage?

July 18, 2017
Aggressive combination treatments for high blood pressure that are intended to protect the kidneys may actually be damaging the organs, new research from the University of Virginia School of Medicine suggests.

Quantifying effectiveness of treatment for irregular heartbeat

July 17, 2017
In a small proof-of-concept study, researchers at Johns Hopkins report a complex mathematical method to measure electrical communications within the heart can successfully predict the effectiveness of catheter ablation, the ...

Concerns over side effects of statins stopping stroke survivors taking medication

July 17, 2017
Negative media coverage of the side effects associated with taking statins, and patients' own experiences of taking the drugs, are among the reasons cited by stroke survivors and their carers for stopping taking potentially ...

Study discovers anticoagulant drugs are being prescribed against safety advice

July 17, 2017
A study by researchers at the University of Birmingham has shown that GPs are prescribing anticoagulants to patients with an irregular heartbeat against official safety advice.

Protein may protect against heart attack

July 14, 2017
DDK3 could be used as a new therapy to stop the build-up of fatty material inside the arteries

Heart study finds faulty link between biomarkers and clinical outcomes

July 14, 2017
Surrogate endpoints (biomarkers), which are routinely used in clinical research to test new drugs, should not be trusted as the ultimate measure to approve new health interventions in cardiovascular medicine, according to ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.