In preemies, maternal smoking tied to necrotizing enterocolitis

June 11, 2012
In preemies, maternal smoking tied to necrotizing enterocolitis
Maternal smoking has been identified as a risk factor associated with the development of necrotizing enterocolitis in premature infants, according to a study published June 11 in Pediatrics.

(HealthDay) -- Maternal smoking has been identified as a risk factor associated with the development of necrotizing enterocolitis (NEC) in premature infants, according to a study published June 11 in Pediatrics.

Cynthia D. Downard, M.D., from the University of Louisville in Kentucky, and colleagues reviewed the medical records of infants with NEC identified from a unit database as well as the prenatal and delivery record of the patient's mother. Each of 73 neonates with NEC was matched to two neonate controls who were treated at the same institution.

The researchers found that maternal cigarette smoking correlated significantly with the development of NEC (P = 0.02). There was no correlation seen between maternal gestational diabetes, maternal hypertension, formula feeding, and pathologic chorioamnionitis or uteroplacental insufficiency and NEC.

"These data identified maternal cigarette smoking as the only risk factor that is associated with the development of NEC in premature infants," the authors write. "Our data imply that smoking delivers toxins and nicotine to the uterine microenvironment that can affect microvascular development and may predispose the fetus to future NEC."

The study was funded by the James R. Petersdorf Fund of Norton Healthcare.

Explore further: Life-threatening condition in preemies linked to blood type

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Life-threatening condition in preemies linked to blood type

November 21, 2011
Many premature infants suffer a life-threatening destruction of intestinal tissue called necrotizing enterocolitis (NEC).

Formula-fed preemies at higher risk for dangerous GI condition than babies who get donor milk

May 1, 2011
Extremely premature babies fed human donor milk are less likely to develop the dangerous intestinal condition necrotizing enterocolitis (NEC) than babies fed a standard premature infant formula derived from cow's milk, according ...

Immune system implicated in prematurity complication

March 19, 2012
Despite advances in neonatal care, necrotizing enterocolitis (NEC) – the most common gastrointestinal emergency in premature infants – continues to be a deadly disease.

Recommended for you

Baby brains help infants figure it out before they try it out

January 17, 2018
Babies often amaze their parents when they seemingly learn new skills overnight—how to walk, for example. But their brains were probably prepping for those tasks long before their first steps occurred, according to researchers.

NeuroNext biomarker study explores natural history of infantile-onset SMA

January 9, 2018
Research led by The Ohio State University Wexner Medical Center to define the natural history of infantile-onset spinal muscular atrophy (SMA) has been "critical" to accelerate the development of effective therapies and hasten ...

No link between childhood lead levels, later criminality

December 27, 2017
(HealthDay)— Exposure to higher levels of lead during early childhood can affect neurological development—but does that mean affected kids are doomed to delinquency?

Early puberty in girls may take mental health toll

December 26, 2017
(HealthDay)—A girl who gets her first menstrual period early in life—possibly as young as 7—has a greater risk for developing depression and antisocial behaviors that last at least into her 20s, a new study suggests.

Technology not taking over children's lives despite screen-time increase

December 21, 2017
With children spending increasing amounts of time on screen-based devices, there is a common perception that technology is taking over their lives, to the detriment and exclusion of other activities. However, new Oxford University ...

Higher blood sugar in early pregnancy raises baby's heart-defect risk

December 15, 2017
Higher blood sugar early in pregnancy raises the baby's risk of a congenital heart defect, even among mothers who do not have diabetes, according to a study led by researchers at the Stanford University School of Medicine.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.