Prevalence, predictors of interval colorectal cancer ID'd

June 8, 2012
Prevalence, predictors of interval colorectal cancer ID'd
A variety of procedural and biologic factors contribute to the development of interval colorectal cancers, seen in 7.2 percent of Medicare beneficiaries, according to a study published in the June 15 issue of Cancer.

(HealthDay) -- A variety of procedural and biologic factors contribute to the development of interval colorectal cancers, seen in 7.2 percent of Medicare beneficiaries, according to a study published in the June 15 issue of Cancer.

Gregory S. Cooper, M.D., of the University Hospitals Case Medical Center in Cleveland, and colleagues identified 57,839 patients aged 69 and older diagnosed with colorectal cancer from the linked Surveillance, Epidemiology, and End Results-Medicare database. The frequency and predictors of colorectal cancer cases that develop after a negative colonoscopy (interval cancer) were assessed.

The researchers found that the overall prevalence of interval cancer was 7.2 percent. Proximal tumor location, increased comorbidity, a previous diagnosis of diverticulosis, and having previously undergone a polypectomy all correlated significantly with interval cancer. At the level of the endoscopist, significant risk factors for interval cancer included lower polypectomy rate, higher volume, and specialty other than gastroenterology.

"A significant proportion of patients developed interval colorectal cancer, particularly in the proximal colon," the authors write. "Contributing factors likely included both procedural and biologic factors, emphasizing the importance of meticulous examination of the ."

Explore further: Physicians who play Mozart while performing colonoscopy may improve adenoma detection rate

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Physicians who play Mozart while performing colonoscopy may improve adenoma detection rate

October 31, 2011
Physicians who listen to Mozart while performing colonoscopy may increase their detection rates of precancerous polyps, according to the results of a new study unveiled today at the American College of Gastroenterology's ...

Thiazolidinediones tied to lower cancer risk in diabetes patients

April 27, 2012
(HealthDay) -- Thiazolidinediones are associated with a lower risk of liver and colorectal cancer in patients with type 2 diabetes, according to a study published in the May issue of Hepatology.

ACP releases new colorectal cancer screening guidance statement

March 5, 2012
The American College of Physicians (ACP) today issued a new guidance statement for colorectal cancer screening. Colorectal cancer is the second leading cause of cancer-related deaths for men and women in the United States. ...

Recommended for you

'Bet hedging' explains the efficacy of many combination cancer therapies

December 14, 2017
The efficacy of many FDA-approved cancer drug combinations is not due to synergistic interactions between drugs, but rather to a form of "bet hedging," according to a new study published by Harvard Medical School researchers ...

Scientists unlock structure of mTOR, a key cancer cell signaling protein

December 14, 2017
Researchers in the Sloan Kettering Institute have solved the structure of an important signaling molecule in cancer cells. They used a new technology called cryo-EM to visualize the structure in three dimensions. The detailed ...

Liquid biopsy results differed substantially between two providers

December 14, 2017
Two Johns Hopkins prostate cancer researchers found significant disparities when they submitted identical patient samples to two different commercial liquid biopsy providers. Liquid biopsy is a new and noninvasive alternative ...

Testing the accuracy of FDA-approved and lab-developed cancer genetics tests

December 14, 2017
Cancer molecular testing can drive clinical decision making and help a clinician determine if a patient is a good candidate for a targeted therapeutic drug. Clinical tests for common cancer causing-mutations in the genes ...

Newest data links inflammation to chemo-brain

December 14, 2017
Inflammation in the blood plays a key role in "chemo-brain," according to a published pilot study that provides evidence for what scientists have long believed.

One in five young colon cancer patients have genetic link

December 13, 2017
As doctors grapple with increasing rates of colorectal cancers in young people, new research from the University of Michigan may offer some insight into how the disease developed and how to prevent further cancers. Researchers ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.