Don't trust liposomes in your beauty products

February 19, 2013, University of Southern Denmark

New research shows that liposomes in cremes are not capable of transporting active ingredients into the skin.

Liposomes are small fat capsules, often added to . According to the beauty industry liposomes are capable of transporting active ingredients deep into the skin and release the active ingredients so that they can alter the skin´s structure by rejuvenating and smoothing the skin.

Research from University of Southern Denmark now shows that liposomes are not capable of transporting themselves deep into the skin, and thus they are not capable of transporting active ingredients deep into the skin.

"We have shown that liposomes are destroyed before they enter the skin or very soon after. When a liposome is destroyed, it spills its cargo of active ingredients. Liposomes are therefore not efficient carriers for transdermal delivery", says professor Luis Bagatolli from Membrane Biophysics and Biophotonics Group/MEMPHYS Center for Biomembrane Physics, Department of Biochemistry and Molecular Biology, University of Southern Denmark.

The researchers used the technique RICS (Raster Imaging Correlation Spectroscopy) to investigate how liposomes labeled with two fluorescent colors move once they are applied to the skin.

"Concerted movement of the two colors should provide evidence that the liposomes are intact when they reach their destination under the skin. We did not observe concerted movement after applying the liposomes to the skin", says Bagatolli.

Previous research done with other techniques has indicated that liposomes are efficient carriers.

"Previous research done with a different technique provide some hints, but not conclusive evidence, that liposomes are capable of penetrating the skin. Therefore some scientists have concluded that liposomes are efficient carriers. Now for the first time we have conclusive evidence that this is not the case", explains Luis Bagatolli.

He now advises buyers of beauty products to not trust the claims that liposomes can carry active ingredients into the skin.

Professor Bagatolli is an expert in biological membranes.

"The human is designed to prevent external components to enter the human body. It is natural, that it also prevents to enter", he explains.

Explore further: Could engineered fatty particles help prevent AIDS?

More information: Journal of Investigative Dermatology www.nature.com/jid/journal/vao … ull/jid2012461a.html

Related Stories

Could engineered fatty particles help prevent AIDS?

September 19, 2011
Could engineered fatty particles help prevent AIDS? Liposomes block HIV infection in early tests; could be a cost-effective preventive for developing countries

Recommended for you

Bioengineered soft microfibers improve T-cell production

January 18, 2018
T cells play a key role in the body's immune response against pathogens. As a new class of therapeutic approaches, T cells are being harnessed to fight cancer, promising more precise, longer-lasting mitigation than traditional, ...

Weight flux alters molecular profile, study finds

January 17, 2018
The human body undergoes dramatic changes during even short periods of weight gain and loss, according to a study led by researchers at the Stanford University School of Medicine.

Secrets of longevity protein revealed in new study

January 17, 2018
Named after the Greek goddess who spun the thread of life, Klotho proteins play an important role in the regulation of longevity and metabolism. In a recent Yale-led study, researchers revealed the three-dimensional structure ...

The HLF gene protects blood stem cells by maintaining them in a resting state

January 17, 2018
The HLF gene is necessary for maintaining blood stem cells in a resting state, which is crucial for ensuring normal blood production. This has been shown by a new research study from Lund University in Sweden published in ...

Magnetically applied MicroRNAs could one day help relieve constipation

January 17, 2018
Constipation is an underestimated and debilitating medical issue related to the opioid epidemic. As a growing concern, researchers look to new tools to help patients with this side effect of opioid use and aging.

Researchers devise decoy molecule to block pain where it starts

January 16, 2018
For anyone who has accidentally injured themselves, Dr. Zachary Campbell not only sympathizes, he's developing new ways to blunt pain.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.