MRSA colonization in groin tied to clinical infections

March 26, 2013

MRSA colonization in groin tied to clinical infections
Groin colonization of methicillin-resistant Staphylococcus aureus (MRSA) leads to an increased risk of developing active MRSA infection later among HIV-infected patients, according to a study published in the April issue of Emerging Infectious Diseases.
(HealthDay)—Groin colonization of methicillin-resistant Staphylococcus aureus (MRSA) leads to an increased risk of developing active MRSA infection later among HIV-infected patients, according to a study published in the April issue of Emerging Infectious Diseases.

Philip J. Peters, M.D., from the U.S. Centers for Disease Control and Prevention in Atlanta, and colleagues enrolled HIV-infected adults in a . Swab specimens collected from the nares and groin were cultured for S. aureus at baseline and at six and 12 months.

The researchers found that MRSA colonization was seen in 13 to 15 percent of HIV-infected participants (98 percent male) at baseline, six months, and 12 months. Nares-only MRSA colonization (41 percent), groin-only (21 percent), and colonization at both sites (38 percent) were detected. MRSA clinical infections occurred 29 times in 25 participants over a median of 2.1 years of follow-up. MRSA clinical infection was significantly associated with MRSA colonization of the groin (adjusted risk ratio, 4.8) and a history of (adjusted risk ratio, 3.1).

"MRSA that can effectively prevent or eliminate groin colonization are likely necessary to reduce clinical infections in this population," the authors write.

Explore further: Impact of MRSA nasal colonization on surgical site infections after gastrointestinal surgery

More information: Full Text

Related Stories

Impact of MRSA nasal colonization on surgical site infections after gastrointestinal surgery

May 20, 2012
Methicillin-resistant Staphylococcus (MRSA) nasal colonization is associated with longer hospital stays and an increase in surgical site infections (SSI) in patients undergoing major gastrointestinal surgery, according to ...

Families of kids with staph infections have high rate of drug-resistant germ

June 4, 2012
Family members of children with a staph infection often harbor a drug-resistant form of the germ, although they don't show symptoms, a team of researchers from Washington University School of Medicine in St. Louis has found.

MRSA skin infections up, linked to furunculosis

July 27, 2012
(HealthDay) -- The incidence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) in the United States is increasing and is associated with follicular infection, most commonly folliculitis followed ...

Recommended for you

New hope for cystic fibrosis

October 19, 2018
A new triple-combination drug treatment being trialled at the Mater Hospital in Brisbane could increase the life expectancy of patients with cystic fibrosis.

Bug guts shed light on Central America Chagas disease

October 18, 2018
In Central America, Chagas disease, or American trypanosomiasis, is spread by the "kissing bug" Triatoma dimidiata. By collecting DNA from the guts of these bugs, researchers reporting in PLOS Neglected Tropical Diseases ...

Rapid genomic sequencing of Lassa virus in Nigeria enabled real-time response to 2018 outbreak

October 18, 2018
Mounting a collaborative, real-time response to a Lassa fever outbreak in early 2018, doctors and scientists in Nigeria teamed up with researchers at Broad Institute of MIT and Harvard and colleagues to rapidly sequence the ...

Infectious disease consultation significantly reduces mortality of patients with bloodstream yeast infections

October 17, 2018
In a retrospective cohort study conducted at the University of Alabama at Birmingham Division of Infectious Diseases, patients with candidemia—a yeast infection in the bloodstream—had more positive outcomes as they relate ...

How drug resistant TB evolved and spread globally

October 17, 2018
The most common form of Mycobacterium tuberculosis (TB) originated in Europe and spread to Asia, Africa and the Americas with European explorers and colonialists, reveals a new study led by UCL and the Norwegian Institute ...

Marker may help target treatments for Crohn's patients

October 16, 2018
Crohn's disease (CD), a chronic inflammatory condition of the intestinal tract, has emerged as a global disease, with rates steadily increasing over the last 50 years. Experts have long suspected that CD likely represents ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.