Chemoprophylaxis found to be safe after spine trauma surgery

July 22, 2013
Chemoprophylaxis found to be safe after spine trauma surgery
Thromboembolic chemoprophylaxis seems to be safe and efficacious in at-risk trauma patients having spinal stabilization surgery, according to a retrospective review published in the July 15 issue of Spine.

(HealthDay)—Thromboembolic chemoprophylaxis seems to be safe and efficacious in at-risk trauma patients having spinal stabilization surgery, according to a retrospective review published in the July 15 issue of Spine.

Lloydine J. Jacobs, M.D., from the University of Pittsburgh Medical Center, and colleagues retrospectively reviewed cases of 227 patients with spinal trauma who underwent surgical stabilization (2009 and 2010) at a single level 1 trauma center. Patients who underwent solely decompressive procedures, non-instrumented fusions, or were excluded.

The researchers found that 56 patients were not treated with chemoprophylaxis and 171 were treated. Postoperative thromboembolism was seen in eight patients in the untreated group (14.3 percent) and 12 patients in the treated group (7 percent; P = 0.096), while occurred in one and four patients, respectively. One untreated patient and 5.3 percent of the treated group required surgical irrigation and debridement for wound drainage. No epidural hematomas were seen in either group. More spinal levels were fused (P = 0.46) and significantly higher injury severity scores (P = 0.001) and longer hospitalizations (P = 0.018) were seen in the treated group. Significantly higher body mass indexes (P = 0.01), injury severity scores (P = 0.001), number of spinal levels fused (P = 0.004), incidence of neurological deficits (P = 0.001), and longer hospitalizations (P = 0.16) were seen in patients who developed postoperative thromboembolism.

"The use of appears to be safe in at-risk patients in the immediate postoperative period after spinal trauma surgery," the authors write.

Explore further: Cervical disc-level canal diameter predicts spinal injury

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Cervical disc-level canal diameter predicts spinal injury

June 13, 2013
(HealthDay)—Disc-level canal diameter determined from magnetic resonance imaging (MRI) can identify patients at risk for acute spinal cord injury (SCI) after minor trauma, according to a study published in the June issue ...

Study examines opiate use in orthopedic trauma patients

June 27, 2013
(HealthDay)—Orthopedic trauma patients with isolated musculoskeletal injuries are significantly more likely than the general population to have used prescription opiates prior to injury, and pre-injury use predicts prolonged ...

Epidural during/Post spine surgery gives better outcomes

July 17, 2013
(HealthDay)—In patients undergoing reconstructive spine surgery, combined epidural and general anesthesia results in better pain control and other outcomes compared with general anesthesia plus narcotics, according to a ...

Fusion rate up for lumbar spinal stenosis, 2004 to 2009

June 13, 2013
(HealthDay)—For patients hospitalized for lumbar spinal stenosis (LSS), the rate of fusions significantly increased and the rate of decompressions significantly decreased from 2004 to 2009 in the United States, according ...

Radiography unnecessary after spinal fusion surgery

September 17, 2012
(HealthDay)—In patients who have undergone spinal fusion surgery with intraoperative fluoroscopic guidance and have no postoperative problems, postoperative radiographs do not provide additional clinical information and ...

Racial disparities exist in outcomes of spinal surgery

June 18, 2013
(HealthDay)—The rate of complications, length of stay, and costs associated with surgery for lumbar spinal stenosis differ for African-American patients compared with white patients, according to research published in the ...

Recommended for you

Drug may help surgical patients stop opioids sooner

December 13, 2017
(HealthDay)—Opioid painkillers after surgery can be the first step toward addiction for some patients. But a common drug might cut the amount of narcotics that patients need, a new study finds.

Children best placed to explain facts of surgery to patients, say experts

December 13, 2017
Getting children to design patient information leaflets may improve patient understanding before they have surgery, finds an article in the Christmas issue of The BMJ.

Burn victim saved by skin grafts from identical twin (Update)

November 23, 2017
A man doomed to die after suffering burns across 95 percent of his body was saved by skin transplants from his identical twin in a world-first operation, French doctors said Thursday.

Is a common shoulder surgery useless?

November 21, 2017
(HealthDay)—New research casts doubt on the true effectiveness of a common type of surgery used to ease shoulder pain.

Study shows electric bandages can fight biofilm infection, antimicrobial resistance

November 6, 2017
Researchers at The Ohio State University Wexner Medical Center have shown - for the first time - that special bandages using weak electric fields to disrupt bacterial biofilm infection can prevent infections, combat antibiotic ...

Obesity increases incidence, severity, costs of knee dislocations

November 3, 2017
A new study of more than 19,000 knee dislocation cases in the U.S. between 2000 and 2012 provides a painful indication of how the nation's obesity epidemic is changing the risk, severity and cost of a traumatic injury.


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.