Review defines new fracture risk factors post-vertebroplasty

July 26, 2013
Review defines new fracture risk factors post-vertebroplasty
Patients with low bone mineral density, low body mass index, and intradiscal cement leakage are at risk for new osteoporotic vertebral compression fractures after vertebroplasty, according to a review published in the June issue of the Journal of Spinal Disorders & Techniques.

(HealthDay)—Patients with low bone mineral density (BMD), low body mass index (BMI), and intradiscal cement leakage are at risk for new osteoporotic vertebral compression fractures (VCFs) after vertebroplasty, according to a review published in the June issue of the Journal of Spinal Disorders & Techniques.

Zitao Zhang, Ph.D., from The First Affiliated Hospital of Nanjing Medical University in China, and colleagues conducted a systematic review and meta-analysis to examine risk factors for new osteoporotic VCFs following . Sixteen studies comprising 559 cases and 1,736 controls were included in the analyses.

The researchers found that low BMD (standardized mean difference [SMD], ?0.73); low BMI (SMD, ?0.30); and intradiscal cement leakage (odds ratio [OR], 2.13) were significant risk factors for new VCFs. These were also significant risk factors for new VCFs adjacent to the treated VCF (SMD, ?0.43; SMD, ?0.52; and OR, 2.61, respectively). For new VCFs away from the original VCF, none of low BMD, low BMI, intradiscal cement leakage, cement volume, surgical approach, age, sex, or thoracolumbar junction fracture were significant risk factors. Dynamic characteristics were reported as risk factors for new VCFs in one study.

"The results of this meta-analysis strongly suggested that patients with low BMD, low BMI, and intradiscal cement leakage were at high risk for new VCFs after vertebroplasty, and risk-reduction options should be considered for such patients," the authors write.

Explore further: Kyphoplasty superior to vertebroplasty for vertebral fx

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Kyphoplasty superior to vertebroplasty for vertebral fx

August 27, 2012
(HealthDay)—For people with osteoporotic vertebral compression fractures, kyphoplasty (KP) is superior to vertebroplasty (VP) for correcting kyphosis, restoring vertebral height, and preventing leakage of bone cement, according ...

Vertebroplasty reportedly provides better pain relief and function

July 9, 2012
An analysis of published data in the medical literature has found that vertebroplasty can provide more pain relief and better function for patients with osteoporotic vertebral compression fractures than nonoperative treatments. ...

Study tracks variation between hospitals in vena cava filter use

March 18, 2013
The frequency of vena cava filter (VCF) use to prevent migration of blood clots to the lungs in patients with acute venous thromboembolism (VTE) appears to vary widely and be associated with which hospital provides the patient ...

Recommended for you

Yeast species used in food industry causes disease in humans

July 19, 2018
A major cause of drug-resistant clinical yeast infections is the same species previously regarded as non-pathogenic and commonly used in the biotechnology and food industries. The study, published on July 19th in the open-access ...

Deadly Rift Valley fever: New insight, and hope for the future

July 19, 2018
Health control measures alone could be ineffective in the long term fight against the deadly Rift Valley fever which affects both humans and animals, a new study in the journal PNAS reports.

New guidelines to diagnose, manage rare endocrine disorders

July 19, 2018
International guidelines have been published for the first time to help doctors around the globe diagnose and manage patients with a very rare set of endocrine diseases known as pseudohypoparathyroidism and its related disorders, ...

Overuse of antibiotics not what the doctor ordered

July 19, 2018
With increased use of antibiotics worldwide linked to growing antibiotic resistance, a world-first study co-authored by a QUT researcher has highlighted the growing impact of non-prescription supply of antibiotics in community ...

Alcohol-related cirrhosis deaths skyrocket in young adults

July 18, 2018
Deaths from cirrhosis rose in all but one state between 1999-2016, with increases seen most often among young adults, a new study shows.

Hidden blood in feces may signal deadly conditions

July 17, 2018
(HealthDay)—Even if it's not visible to the naked eye, blood in the stool can be serious—a sign of a potentially fatal disease other than colon cancer, new research suggests.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.