Medication adherence after hospitalization for acute coronary syndrome

November 18, 2013, The JAMA Network Journals

Patients better adhered to their medication regimens in the year following hospitalization for acute coronary syndrome (ACS) when they were part of a program that included personalized attention from a pharmacist compared with usual care, according to a study by P. Michael Ho, M.D., Ph.D., of the Denver VA Medical Center, and colleagues.

Previous studies have found that adherence to cardioprotective is poor after are discharged from the hospital, with one-third of patients discontinuing at least one medication by mouth by one month.

Researchers randomized 253 patients from four Department of Veterans Affairs medical centers in Denver, Seattle, Durham, N.C., and Little Rock, Ark., to usual care or an intervention that included direct contact with a pharmacist to discuss medications shortly after discharge, patient education, collaboration between a patient's and physician, and voice messaging reminders. The intervention cost about $360 per patient.

The study was completed by 241 patients (122 in the intervention and 119 in usual care) and researchers measured the proportion of patients adhering to their , along with the proportion achieving blood pressure and low-density lipoprotein cholesterol (LDL-C) level targets.

Study findings indicate the intervention increased adherence to mediation regimens (89.3 percent in the intervention vs. 73.9 percent in the usual care group) but there was no difference in the proportion of patients who achieved BP and LDL-C level goals.

"Additional studies are needed to understand the impact of the magnitude of adherence improvement shown in our study on clinical outcomes prior to broader dissemination of such an adherence program," the authors conclude.

Explore further: Pharmacist intervention does not prevent medication errors

More information: JAMA Intern Med. Published online November 18, 2013. DOI: 10.1001/jamainternmed.2013.12944

Related Stories

Pharmacist intervention does not prevent medication errors

July 3, 2012
(HealthDay) -- A pharmacist-delivered intervention does not significantly improve the rate of clinically important medication errors following discharge among hospitalized heart patients, according to a study published in ...

Texting heart medication reminders improved patient adherence

November 18, 2013
Getting reminder texts helped patients take their heart medicines (anti-platelet and cholesterol-lowering drugs) more regularly, according to research presented at the American Heart Association's Scientific Sessions 2013.

Intervention helps improve and maintain better blood pressure control

July 2, 2013
An intervention that consisted of home blood pressure (BP) telemonitoring with pharmacist management resulted in improvements in BP control and decreases in BP during 12 months, compared with usual care, and improvement in ...

Physicians don't adequately monitor patients' medication adherence

July 16, 2012
Patients' non-adherence to prescribed medication costs the U.S. health care system an estimated $290 billion annually and can lead to poor clinical outcomes, increased hospitalizations and higher mortality.

Hospitalized HIV patients benefit from seeing infectious diseases specialists

October 4, 2013
When patients with HIV are hospitalized for other conditions, such as a heart problem, surgery or complications of diabetes, mistakes are often made involving their complicated anti-retroviral therapy (ART) regimens. But ...

Single combination pill provides benefit to patients with or at risk of CVD

September 3, 2013
In a randomized trial that included about 2,000 patients with or at high risk of cardiovascular disease (CVD), use of a fixed-dose combination medication for blood pressure, cholesterol, and platelet control compared to usual ...

Recommended for you

Antibodies linked to heart attacks

October 23, 2018
Levels of antiphospholipid antibodies, which are associated with rheumatic diseases, are also elevated in myocardial infarction without any autoimmune co-morbidity, a study from Karolinska Institutet in Sweden published in ...

Poor oral health linked to higher blood pressure, worse blood pressure control

October 22, 2018
People with high blood pressure taking medication for their condition are more likely to benefit from the therapy if they have good oral health, according to new research in the American Heart Association's journal Hypertension.

No sweat required: Team finds hypertension treatment that mimics effect of exercise

October 16, 2018
Couch potatoes rejoice—there might be a way to get the blood pressure lowering benefits of exercise in pill form.

New model suggests cuffless, non-invasive blood pressure monitoring possible using pulse waves

October 16, 2018
A large team of researchers from several institutions in China and the U.S. has developed a model that suggests it should be possible to create a cuffless, non-invasive blood pressure monitor based on measuring pulse waves. ...

Why heart contractions are weaker in those with hypertrophic cardiomyopathy

October 16, 2018
When a young athlete suddenly dies of a heart attack, chances are high that they suffer from familial hypertrophic cardiomyopathy (HCM). Itis the most common genetic heart disease in the US and affects an estimated 1 in 500 ...

Novel genetic study sheds new light on risk of heart attack

October 12, 2018
Loss of a protein that regulates mitochondrial function can greatly increase the risk of myocardial infarction (heart attack), Vanderbilt scientists reported Oct. 3 in the journal eLife.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.