Low vitamin B12 linked to postural orthostatic tachycardia

December 23, 2013
Low vitamin B<sub>12</sub> linked to postural orthostatic tachycardia

(HealthDay)—During adolescence, low vitamin B12 levels are associated with postural orthostatic tachycardia syndrome (POTS), according to a study published online Dec. 23 in Pediatrics.

Taliha Öner, M.D., from Dr. Behçet Uz Children's Hospital in Izmir, Turkey, and colleagues examined the correlation between vitamin B12 levels and POTS during adolescence. Serum vitamin B12, , and ferritin levels were assessed in 125 patients (mean age, 11.1 years; 60 percent female) reporting short-term loss of consciousness and diagnosed with vasovagal syncope, and 50 control subjects (mean age, 10.94 years; 62 percent female).

The researchers found that patients had significantly lower levels of vitamin B12 versus controls (352.75 versus 411.32 pg/mL; P < 0.001), and that a low vitamin B12 level was significantly more prevalent in the patient versus the control group (47.2 versus 18 percent; P < 0.001). Within the patient group, vitamin B12 levels were significantly lower in children with the POTS pattern than those without the POTS response (P = 0.03).

"Our study shows the association between the etiopathogenesis of POTS and the B12 deficiency-induced sympathetic nervous system-baroreceptor dysfunction," the authors write.

Explore further: Low vitamin B12 levels increase the risk of fractures in older men

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Low vitamin B12 levels increase the risk of fractures in older men

December 11, 2013
Older men who have low levels of vitamin B12 have a higher risk of having fractures. These are the findings of researchers at the Sahlgrenska Academy as a part of an international study of a total of 1000 older men.

Acid-suppressing medications associated with vitamin B12 deficiency

December 10, 2013
Use for 2 or more years of proton pump inhibitors and histamine 2 receptor antagonists (two types of acid-inhibiting medications) was associated with a subsequent new diagnosis of vitamin B12 deficiency, according to a study ...

Preventing vitamin B12 deficiency among vegetarians, vegans and the elderly

July 18, 2013
Older people, vegetarians and vegans should take special care to get enough vitamin B12 through changes in their diets, a review of scientific studies on the vitamin has concluded. In the article, published in ACS' Journal ...

Low vitamin B12 levels may lead to brain shrinkage, cognitive problems

September 26, 2011
Older people with low levels of vitamin B12 in their blood may be more likely to lose brain cells and develop problems with their thinking skills, according to a study published in the September 27, 2011, print issue of Neurology, ...

Higher than normal levels of Vitamin B12 may indicate cancer risk

November 18, 2013
Vitamin B12 (cobalamin [Cbl]) is essential for maintaining healthy bodily function but higher than normal levels (reference range 200-600 pmol/L) may indicate that a patient is at risk of developing certain cancers, according ...

Metformin may increase risk of cognitive impairment

September 21, 2013
(HealthDay)—Metformin may increase the risk of cognitive impairment in patients with diabetes; however, calcium supplementation may attenuate this risk, according to research published online Sept. 5 in Diabetes Care.

Recommended for you

Urgent call for prevention strategies for sleep-related infant deaths

June 22, 2018
Dr. Kyran Quinlan and colleagues at Rush issue an urgent call for prevention strategies for sleep-related infant deaths in his viewpoint, "Protecting Infants From Sleep-Related Deaths" published in the June 18 online issue ...

Infant colic leads to no ongoing problems, study shows

June 21, 2018
Colicky babies whose crying eases within three months have no ongoing behavioural problems according to new research by the Murdoch Children's Research Institute (MCRI).

Diagnosing and treating disorders of early sex development

June 19, 2018
Diagnosing, advising on and treating disorders of early sex development represent a huge medical challenge, both for those affected and for treating physicians. In contrast to the earlier view, DSD (Difference of Sex Development) ...

Use of alternative medicines has doubled among kids, especially teens

June 18, 2018
A new study published in JAMA Pediatrics shows that since 2003, the use of alternative medicines, such as herbal products and nutraceuticals, among children has doubled. The University of Illinois at Chicago researchers who ...

Virtual reality headsets significantly reduce children's fear of needles

June 18, 2018
The scenario is all too familiar for the majority of parents. The crying, the screaming and the tantrums as they try to coax their children into the doctor's office for routine immunizations. After all, who can't relate to ...

Both quantity and quality of sleep affect cardiovascular risk factors in adolescents

June 15, 2018
A study from a research team led by a MassGeneral Hospital for Children (MGHfC) physician finds that both the quantity and quality of sleep—the amount of time spent sleeping and the percentage of sleep that is undisturbed—in ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.