Stellate ganglion blockade cuts menopause symptoms

February 14, 2014
Stellate ganglion blockade cuts menopause symptoms

(HealthDay)—For postmenopausal women, stellate ganglion blockade (SGB) significantly reduces objective measures of vasomotor symptoms (VMS), according to a study published online Feb. 3 in Menopause.

David R. Walega, M.D., from the Feinberg School of Medicine at Northwestern University in Chicago, and colleagues randomized 40 (aged 30 to 70 years) with moderate to severe VMS to image-guided SGB (performed with 5 mL of 0.5 percent bupivacaine) or sham injection of saline to the subcutaneous neck tissues. VMS were noted at baseline and for six months. Ambulatory sternal skin conductance monitoring was used to measure objective VMS over a 24-hour period at baseline and on three-month follow-up.

The researchers found that, while there were no significant between-group differences in overall VMS frequency, in the active group, there was a greater reduction in the frequency of moderate to very severe VMS compared with the sham treatment group (event rate ratio, 0.50; P < 0.001). In the SGB group, the frequency of objective VMS was further reduced compared with the sham group (event rate ratio, 0.71; P < 0.05). No study-related serious adverse events were reported.

"SGB may provide effective treatment of VMS in who seek nonhormonal treatments because of safety concerns and personal preference," the authors write. "The finding that SGB significantly reduces objectively measured VMS provides further evidence of efficacy."

Several authors disclosed financial ties to the pharmaceutical industry.

Explore further: Self-evaluation of menopausal symptoms underestimates true burden, study finds

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Self-evaluation of menopausal symptoms underestimates true burden, study finds

July 25, 2013
Physicians should consider a more in-depth evaluation of their menopausal patients' symptoms, as current approaches might not accurately reflect the number of hot flashes and night sweats each woman experiences, a new University ...

Nerve block eases troublesome hot flashes

February 5, 2014
Injecting a little anesthetic near a nerve bundle in the neck cut troublesome hot flashes significantly, shows a new randomized, controlled trial published online today in Menopause, the journal of The North American Menopause ...

Research finds severe hot flashes reduced with quick neck injection

October 31, 2013
A shot in the neck of local anesthesia may reduce hot flashes by as much as 50 percent for at least six months, a recent Northwestern Medicine study found.

Could a neck injection ease tough-to-bear hot flashes?

October 13, 2013
(HealthDay)—A shot in the neck may curb extreme hot flashes associated with menopause, a small new study suggests.

Romosozumab increases bone mineral density post-menopause

January 6, 2014
(HealthDay)—Romosozumab seems safe and effective for increasing bone mineral density in postmenopausal women with low bone mineral density, according to a study published online Jan. 1 in the New England Journal of Medicine.

Recommended for you

Hormone from fat tissue can give protection against polycystic ovary syndrome

August 10, 2017
Obesity and reduced insulin sensitivity are common in polycystic ovary syndrome, PCOS. New research based on animal studies, and to be published in the journal PNAS, reveals that the hormone adiponectin can protect against ...

Study in mice may reveal insights into causes of miscarriages for some women

August 9, 2017
Researchers at St. Michael's Hospital have identified how natural killer cells in the mouse placenta can cause a fetus to fail to grow in the womb or cause miscarriages.

Insomnia, sleep apnea nearly double the risk of preterm delivery before 34 weeks

August 9, 2017
Pregnant women who are diagnosed with sleep disorders such as sleep apnea and insomnia appear to be at risk of delivering their babies before reaching full term, according to an analysis of California births by researchers ...

Elective freezing of IVF embryos linked to higher pregnancy rates in some cases

August 1, 2017
A delay in transferring embryos to the mother improves the success of in vitro fertilization in certain cases, according to a study by scientists at the Stanford University School of Medicine, Celmatix Inc. and several other ...

Negative birth outcomes linked to air pollution exposure early in pregnancy, study finds

July 27, 2017
Exposure to air pollution early in a pregnancy could increase risk for preterm birth and low birth weight, according to a study led by researchers at NYU School of Medicine, and published on July 27 in Environmental Health ...

Study shows a significant ongoing decline in sperm counts of Western men

July 25, 2017
In the first systematic review and meta-analysis of trends in sperm count, researchers from the Hebrew University-Hadassah Braun School of Public Health and Community Medicine and the Icahn School of Medicine at Mount Sinai ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.