High prevalence of anal HPV in men who have sex with men

May 8, 2014
High prevalence of anal HPV in men who have sex with men

(HealthDay)—For men who have sex with men (MSM), the prevalence of anal human papillomavirus (HPV) infection is high, according to a study published online March 23 in HIV Medicine.

Corinna Sadlier, M.D., from St. James's Hospital in Dublin, and colleagues examined the molecular epidemiology of HPV infection in a cohort of 194 HIV-positive and HIV-negative MSM aged older than 18 years. Anal swabs were collected and anal HPV infection identified using a assay.

The researchers detected HPV DNA in 113 individuals, of whom 42 percent had a high-risk (HR) HPV type. HR HPV types 16, 18, and 31 were detected in 27, 16, and 23 percent of samples, respectively. Seventeen percent of individuals had more than one type of HR HPV. The prevalence of HPV and HR HPV were higher in those aged older than 30 years (P = 0.001 and 0.028, respectively). Compared with HIV-negative individuals, HIV-positive participants were more likely to have any detectable HPV (77 versus 61 percent; P = 0.04); to have HR HPV 18 or 31 (P = 0.05 and 0.006, respectively); and to be infected with more than one type of HPV (31 versus 3 percent; P < 0.001).

"Emerging patterns of HPV-related disease strengthen the call for universal vaccination of boys and girls with consideration of catch-up and targeted vaccination of high-risk groups such as MSM and those with HIV infection," the authors write.

Explore further: Pre-HPV vaccine, most oropharyngeal cancers HPV+

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Pre-HPV vaccine, most oropharyngeal cancers HPV+

April 22, 2014
(HealthDay)—Most oropharyngeal cancers in the United States diagnosed between 1995 and 2005 were positive for human papillomavirus (HPV), specifically HPV 16 or 18, according to a study published in the May issue of the ...

Reduction in HPV in young women in England seen, following national immunization program

April 13, 2014
Each year around 2,000-2,500 women are diagnosed with cervical cancer in England, the most common cancer in women under 35. Infection with high-risk human papillomavirus (HR HPV) types 16 and 18 is responsible for around ...

Increased anal cancer risk from HIV plus HPV dual infection

December 3, 2013
(Medical Xpress)—Human papillomavirus, or HPV, which can cause cervical cancer in women, is also known to cause anal cancer in both women and men. Now, a study led by researchers at the UCLA School of Nursing has found ...

Extend HPV jab to young gay men, say sexual health experts

July 15, 2013
The vaccination programme against HPV infection began in 2008 in the UK, but only among girls, on the grounds that this would curb the spread of the infection to boys as well.

HIV-positive men show high rates of papillomavirus infection at oral, anal and penile sites

June 27, 2013
(Medical Xpress)—Scientists in Barcelona have found a high presence of papillomavirus infection in oral, anal and penile cavities in HIV-positive men, particularly in the anal cavities of men who have homosexual sex. The ...

Most anal lesions don't cause cancer in men, research shows

March 23, 2012
(HealthDay) -- Anal human papillomavirus (HPV) infection and precancerous lesions are common among gay and bisexual men, but most of these cases will not progress to anal cancer, a new analysis of earlier research shows.

Recommended for you

Study provides insight into link between two rare tumor syndromes

August 22, 2017
UCLA researchers have discovered that timing is everything when it comes to preventing a specific gene mutation in mice from developing rare and fast-growing cancerous tumors, which also affects young children. This mutation ...

Retaining one normal BRCA gene in breast, ovarian cancers influences patient survival

August 22, 2017
Determining which cancer patients are likely to be resistant to initial treatment is a major research effort of oncologists and laboratory scientists. Now, ascertaining who might fall into that category may become a little ...

Study identifies miR122 target sites in liver cancer and links a gene to patient survival

August 22, 2017
A new study of a molecule that regulates liver-cell metabolism and suppresses liver-cancer development shows that the molecule interacts with thousands of genes in liver cells, and that when levels of the molecule go down, ...

Zebrafish larvae could be used as 'avatars' to optimize personalized treatment of cancer

August 21, 2017
Portuguese scientists have for the first time shown that the larvae of a tiny fish could one day become the preferred model for predicting, in advance, the response of human malignant tumors to the various therapeutic drugs ...

Scientists discover vitamin C regulates stem cell function, curbs leukemia development

August 21, 2017
Not much is known about stem cell metabolism, but a new study from the Children's Medical Center Research Institute at UT Southwestern (CRI) has found that stem cells take up unusually high levels of vitamin C, which then ...

Searching for the 'signature' causes of BRCAness in breast cancer

August 21, 2017
Breast cancer cells with defects in the DNA damage repair-genes BRCA1 and BRCA2 have a mutational signature (a pattern of base swaps—e.g., Ts for Gs, Cs for As—throughout a genome) known in cancer genomics as "Signature ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.