Laser therapy on the repair of a large-gap transected sciatic nerve in a reinforced nerve conduit

July 24, 2014

Researchers at Central Taiwan University of Science and Technology, Taiwan, led by Prof. Liu, Dr. Shen and Mrs. Yang have developed a biodegradable nerve conduit containing genipin-cross-linked gelatin was annexed using beta-tricalcium phosphate (TCP) ceramic particles (Genipin-Gelatin-TCP, GGT) to bridge the transection of a 15 mm sciatic nerve in rats. The effects of LLL therapy on peripheral nerve restoration and regeneration have systematically investigated throughout the study period.

Very few studies have employed tubulation in combination with diode laser therapy to repair . Furthermore, very few researchers have investigated the influence of LLL therapy on in a biodegradable nerve conduit.

The study, reported on Neural Regeneration Research (Vol. 9, No.12, 2014), confirmed that combining the GGT nerve conduit with an LLL therapy system may be beneficial for the regeneration of nerves across long gaps, as well as for accelerating the reinnervation rate of nerves and improving recruitment in muscles. These benefits may in turn lead to improve functional and morphologic recovery of peripheral nerves. Further studies on the use of LLL therapy as a noninvasive treatment modality for various nerve diseases and injuries could pave the way for mainstream acceptance and standardization of this innovative therapy.

Explore further: Stem cells injected into nerve guide tubes repair injured peripheral nerve

More information: Neural Regen Res. 2014;9(12): 1180-1182.

Related Stories

Stem cells injected into nerve guide tubes repair injured peripheral nerve

January 9, 2014
Using skin-derived stem cells (SDSCs) and a previously developed collagen tube designed to successfully bridge gaps in injured nerves in rat models, the research team in Milan, Italy that established and tested the procedure ...

Beijing researchers explore liquid metal to reconnect nerves

April 29, 2014
(Medical Xpress)—What is the most effective way to reconnect severed nerves? After years of research, scientists are still exploring, aware of the risks of long-term disability. Techniques used include sewing ends back ...

Race to nerve regeneration: faster is better

October 3, 2011
A team of researchers led by Clifford Woolf and Chi Ma, at Children's Hospital Boston and Harvard Medical School, Boston, has identified a way to accelerate the regeneration of injured peripheral nerves in mice such that ...

Stem cells from muscle can repair nerve damage after injury, researchers show

March 18, 2014
Stem cells derived from human muscle tissue were able to repair nerve damage and restore function in an animal model of sciatic nerve injury, according to researchers at the University of Pittsburgh School of Medicine. The ...

Using stem cells to promote nerve regeneration

October 9, 2013
Johns Hopkins researchers from the Department of Plastic and Reconstructive Surgery report that a type of stem cell found easily in fat cells and also in bone marrow promoted nerve regeneration in rats with paralyzing leg ...

Recommended for you

A sodium surprise: Engineers find unexpected result during cardiac research

July 20, 2017
Irregular heartbeat—or arrhythmia—can have sudden and often fatal consequences. A biomedical engineering team at Washington University in St. Louis examining molecular behavior in cardiac tissue recently made a surprising ...

Want to win at sports? Take a cue from these mighty mice

July 20, 2017
As student athletes hit training fields this summer to gain the competitive edge, a new study shows how the experiences of a tiny mouse can put them on the path to winning.

Engineered liver tissue expands after transplant

July 19, 2017
Many diseases, including cirrhosis and hepatitis, can lead to liver failure. More than 17,000 Americans suffering from these diseases are now waiting for liver transplants, but significantly fewer livers are available.

Lunatic Fringe gene plays key role in the renewable brain

July 19, 2017
The discovery that the brain can generate new cells - about 700 new neurons each day - has triggered investigations to uncover how this process is regulated. Researchers at Baylor College of Medicine and Jan and Dan Duncan ...

'Smart' robot technology could give stroke rehab a boost

July 19, 2017
Scientists say they have developed a "smart" robotic harness that might make it easier for people to learn to walk again after a stroke or spinal cord injury.

New animal models for hepatitis C could pave the way for a vaccine

July 19, 2017
They say that an ounce of prevention is worth a pound of cure. In the case of hepatitis C—a disease that affects nearly 71 million people worldwide, causing cirrhosis and liver cancer if left untreated—it might be worth ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.