Smoking ups pseudarthrosis after 2-level fusion of lumbar spine

Smoking ups pseudarthrosis after 2-level fusion of lumbar spine

(HealthDay)—For patients undergoing posterolateral fusion (PLF) of the lumbar spine, smoking is associated with increased rate of pseudarthrosis among those undergoing two-level, but not single-level, PLF, according to research published in the Oct. 1 issue of Spine.

Mohamad Bydon, M.D., from the Johns Hopkins University School of Medicine in Baltimore, and colleagues conducted a retrospective medical record review involving all who underwent single- and two-level instrumented PLF without interbody devices for degenerative spine disease. Two hundred eighty-one were included from a single institution during a 21-year period. Of the patients, 82.21 percent were and 17.9 percent were . Patients were followed for an average of 53.5 months.

The researchers observed no significant difference in the complication rates for nonsmokers versus smokers (3.57 versus 7.69 percent; P = 0.353) among those undergoing single-level fusion. Pseudarthrosis occurred in 9.82 percent of nonsmokers and 7.69 percent of smokers (P = 0.738). Complication rates were not significantly different for nonsmokers and smokers undergoing two-level PLF (6.72 versus 4.17 percent; P = 0.638), but the smokers group had significantly higher pseudarthrosis rates (29.17 versus 10.92; P = 0.019).

"The findings in this study suggest that smoking has a significant impact on pseudarthrosis rates after two-level PLF of the lumbar spine, but not necessarily on single-level PLF," the authors write.

Relevant financial activities outside the submitted work were disclosed: consultancy, grants, stocks, travel expenses.


Explore further

High mortality, costs with C. difficile after spine surgery

More information: Full Text (subscription or payment may be required)
Journal information: Spine

Copyright © 2014 HealthDay. All rights reserved.

Citation: Smoking ups pseudarthrosis after 2-level fusion of lumbar spine (2014, October 8) retrieved 19 July 2019 from https://medicalxpress.com/news/2014-10-ups-pseudarthrosis-level-fusion-lumbar.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
 shares

Feedback to editors

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more