No negative consequences of guidelines for antibiotic therapy

No negative consequences of guidelines for antibiotic therapy

(HealthDay)—For children with community-acquired pneumonia (CAP), there are no negative consequences associated with use of guideline-recommended antibiotic therapy, according to a study published in the January issue of the Journal of Hospital Medicine.

Joanna Thomson, M.D., M.P.H., from the Cincinnati Children's Hospital Medical Center, and colleagues conducted a involving children aged 3 months to 18 years, hospitalized with CAP. The authors examined the impact of empiric guideline-recommended on outcomes. Length of stay, total hospital costs, and inpatient pharmacy costs were assessed as the primary outcomes.

The researchers found that empiric guideline-recommended therapy was prescribed to 76 percent of 220 patients. There was no significant difference in length of stay (adjusted −5.8 percent change), total costs (adjusted −10.9 percent change), or inpatient pharmacy costs (adjusted 14.8 percent change) among those who did and did not receive guideline-recommended therapy. Secondary outcomes (including broadened antibiotic therapy, emergency department revisits, and readmissions) were rare and did not vary in unadjusted analyses according to receipt of guideline-recommended therapy.

"Our findings highlight the importance of changing antibiotic prescribing practices to reflect , as there was no evidence of negative unintended consequences with our local practice change," the authors write.

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Journal information: Journal of Hospital Medicine

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Citation: No negative consequences of guidelines for antibiotic therapy (2015, January 13) retrieved 5 March 2021 from
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