Daily PrEP prevents HIV infection in high-risk individuals

Daily PrEP prevents HIV infection in high-risk individuals

(HealthDay)—None of 657 patients who took a daily pill to prevent HIV infection contracted the virus over a period of more than two years, according to a study from Kaiser Permanente of San Francisco. The findings, published online Sept. 1 in Clinical Infectious Diseases, dispel concerns that use of pre-exposure prophylaxis (PrEP) would lead to more HIV infections, The New York Times reported.

Gay men accounted for all but four of the patients who took the two-drug combination (emtricitabine and tenofovir [Truvada]), which was approved by the U.S. Food and Drug Administration in mid-2012. The patients were followed from then until February of this year, and 84 percent said they had multiple sexual partners during that time, The Times reported.

More than 40 percent did say they used fewer condoms and some were infected with other such as syphilis, gonorrhea, and chlamydia as a result, but none contracted HIV. "This is very reassuring data," lead author Jonathan Volk, M.D., an epidemiologist at Kaiser Permanente of San Francisco, told The Times. "It tells us that PrEP works even in a high-risk population."

"This shows that the effectiveness of PrEP is really strikingly high," Anthony Fauci, M.D., director of the U.S. National Institute of Allergy and Infectious Diseases, told The Times. "And this study takes it out of the realm of clinical trials and into the real world."


Explore further

Pill taken before, after sex may prevent HIV, study finds

More information: Abstract
Full Text (subscription or payment may be required)
Editorial
Journal information: Clinical Infectious Diseases

Copyright © 2015 HealthDay. All rights reserved.

Citation: Daily PrEP prevents HIV infection in high-risk individuals (2015, September 4) retrieved 12 November 2019 from https://medicalxpress.com/news/2015-09-daily-prep-hiv-infection-high-risk.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
24 shares

Feedback to editors

User comments