Depression linked to CKD in patients with diabetes

July 13, 2016

(HealthDay)—For patients with diabetes, the presence of depression is associated with increased risk of developing chronic kidney disease (CKD), according to a study published online June 16 in Diabetes Care.

Marta Novak, M.D., Ph.D., from the University of Toronto, and colleagues examined the correlation between and incident CKD, mortality, and incident cardiovascular events in U.S. veterans with diabetes. A total of 933,211 patients with diabetes were identified among a nationally representative prospective cohort of more than three million U.S. veterans with baseline estimated (eGFR) of ≥60 mL/min/1.73m². At enrollment, 340,806 patients had depression.

The researchers found that patients with depression were younger, had higher eGFR, and had more comorbidities. Overall, 180,343 patients developed incident CKD. The risk of incident CKD was increased with depression (adjusted hazard ratio, 1.20). Depression was also linked to elevated all-cause mortality (adjusted hazard ratio, 1.25).

"Intervention studies should determine if effective treatment of depression in diabetic patients would prevent major renal and cardiovascular complications," the authors write.

Explore further: Nonalcoholic fatty liver disease linked to CKD in T1DM

More information: Full Text (subscription or payment may be required)

Related Stories

Nonalcoholic fatty liver disease linked to CKD in T1DM

April 9, 2014
(HealthDay)—For patients with type 1 diabetes, nonalcoholic fatty liver disease (NAFLD) is independently associated with the risk of incident chronic kidney disease (CKD), according to a study published online April 2 in ...

Hospitalized patients with CKD often unaware of it

September 16, 2015
(HealthDay)—Hospitalized patients with chronic kidney disease (CKD) frequently are unaware of their condition, according to research published in the September issue of the Journal of Hospital Medicine.

ADA: Empagliflozin linked to reduction in T2DM nephropathy

June 15, 2016
(HealthDay)—For patients with type 2 diabetes at high cardiovascular risk, empagliflozin is associated with a reduction in incident or worsening nephropathy, according to a study published online June 14 in the New England ...

Study assesses bidirectional link for diabetes, depression

November 19, 2012
(HealthDay)—There is a bidirectional relationship between type 2 diabetes and depression, with a stronger correlation for depression predicting diabetes onset, according to research published online Nov. 12 in Diabetes ...

Even short-term T2DM remission reduces risk of microvascular Dz

June 14, 2016
(HealthDay)—For patients with type 2 diabetes, remission after bariatric surgery is associated with a reduced risk of microvascular disease, even after subsequent relapse, according to a study published online June 6 in ...

Nonalbuminuric CKD ups cardiovascular morbidity in T1DM

August 31, 2015
(HealthDay)—Nonalbuminuric chronic kidney disease is associated with increased risk of cardiovascular disease and all-cause mortality, but not renal outcomes, in patients with type 1 diabetes, according to a study published ...

Recommended for you

Type 2 diabetes is not for life

December 5, 2017
Almost half of the patients with Type 2 diabetes supported by their GPs on a weight loss programme were able to reverse their diabetes in a year, a study has found.

Skipping breakfast disrupts 'clock genes' that regulate body weight

November 30, 2017
Irregular eating habits such as skipping breakfast are often associated with obesity, type 2 diabetes, hypertension and cardiovascular disease, but the precise impact of meal times on the body's internal clock has been less ...

Type 2 diabetes has hepatic origins

November 28, 2017
Affecting as many as 650 million people worldwide, obesity has become one of the most serious global health issues. Among its detrimental effects, it increases the risk of developing metabolic conditions, and primarily type ...

Critical link between obesity and diabetes has been identified

November 28, 2017
UT Southwestern researchers have identified a major mechanism by which obesity causes type 2 diabetes, which is a common complication of being overweight that afflicts more than 30 million Americans and over 400 million ...

Controlling diabetes with your phone might be possible someday

November 21, 2017
Think about this. You have diabetes, are trying to control your insulin levels and instead of taking a pill or giving yourself an injection, you click an app on your phone that tells your pancreas to bring blood sugar levels ...

Simple test predicts diabetes remission following weight loss surgery

November 21, 2017
A new simple test that helps predicts which people with type 2 diabetes will benefit most from weight loss surgery has been developed by a UCL-led team.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.