Platelet-rich plasma SIJ injection cuts low back pain

Platelet-rich plasma SIJ injection cuts low back pain

(HealthDay)—For patients with chronic low back pain, ultrasound-guided sacroiliac joint (SIJ) injection with platelet-rich plasma (PRP) is effective for reducing pain, according to a study published online Sept. 27 in Pain Practice.

Varun Singla, M.D., from the Sanjay Gandhi Postgraduate Institute of Medical Sciences in Lucknow, India, and colleagues examined the efficacy and safety of PRP versus methylprednisolone in ultrasound-guided SIJ injection for . Forty patients with chronic low back pain diagnosed with SIJ pathology were randomized into two groups and received either 1.5 mL methylprednisolone and 1.5 mL lidocaine with 0.5 mL saline (Group S) or 3 mL leukocyte-free PRP with 0.5 mL calcium chloride (Group P) in ultrasound-guided SIJ injection.

The researchers found that, compared with Group S, Group P had significantly lower intensity of pain at six weeks and at three months. In Group S the efficacy of steroid injection was reduced to 25 percent at three months, while in Group P it was 90 percent. In patients receiving PRP there was a strong association, and when other factors were controlled there was a reduction of visual analogue scale score ≥50 percent from baseline. There was initial improvement in the Modified Oswestry Disability Questionnaire scores and Short Form Health Survey scores for up to four weeks in Group S, followed by further deterioration at three months; in Group P both scores improved gradually for up to three months.

"The intra-articular PRP injection is an effective treatment modality in low back pain involving SIJ," the authors write.

Explore further

Radiofrequency neurotomy efficient in knee osteoarthritis

More information: Abstract
Full Text (subscription or payment may be required)

Copyright © 2016 HealthDay. All rights reserved.

Citation: Platelet-rich plasma SIJ injection cuts low back pain (2016, October 3) retrieved 28 November 2020 from
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Feedback to editors

User comments