Chorioretinal lesions secondary to zika virus observed

March 13, 2017

(HealthDay)—Acute-onset, self-resolving, placoid or multifocal non-necrotizing chorioretinal lesions may be caused by Zika virus infection, according to a case report published online March 9 in JAMA Ophthalmology.

Christopher R. Henry, M.D., from the University of Miami Miller School of Medicine, and colleagues present the case of a woman in her 60s from Guaynabo, Puerto Rico, who presented with reduced and bilateral diffuse, subretinal, confluent, placoid, and multifocal chorioretinal lesions who was observed over a five-month period.

The authors identified early hypofluorescence and late staining of the chorioretinal lesions on fluorescein angiography. Outer retinal disruption in the placoid macular lesions was demonstrated on . Real-time reverse transcription polymerase chain reaction testing identified Zika RNA in a plasma sample; after ruling out other viral and infectious causes, Zika was suspected as the cause of chorioretinal lesions. The patient's visual acuity had improved to 20/60 oculus dexter (OD) and 20/25 oculus sinister (OS) three weeks after symptom onset, with intraocular pressures of 18 and 19 mm Hg OD and OS, respectively. The chorioretinal lesions had healed in six weeks and visual acuity had improved to 20/25 OD and 20/20 OS.

"Similar findings in potentially exposed adults suggest that clinicians should consider immunoglobulin M antibody or testing for Zika virus as well as diagnostic testing for Dengue fever and West Nile virus," the authors write.

Explore further: Endogenous endophthalmitis ID'd after breast implant surgery

More information: Abstract/Full Text (subscription or payment may be required)

Related Stories

Endogenous endophthalmitis ID'd after breast implant surgery

March 22, 2016
(HealthDay)—In a case report published online March 17 in JAMA Ophthalmology, bilateral endogenous endophthalmitis with chorioretinal involvement due to Candida albicans a few hours after breast augmentation surgery has ...

Eye abnormalities in infants with microcephaly associated with Zika virus

February 9, 2016
Vision-threatening eye abnormalities in infants in Brazil with microcephaly (a birth defect characterized by an abnormally small head) may be associated with presumed intrauterine infection with Zika virus, according to a ...

Zika virus may be linked to more eye problems in Brazilian babies with microcephaly

May 25, 2016
Researchers studying babies with a Zika virus-related birth defect say they have found previously unreported eye problems possibly linked to the virus that could result in severe visual impairment. In three Brazilian infants ...

Zika virus can cause severe damage to retina in infants

November 10, 2016
In a study published online by JAMA Ophthalmology, Rubens Belfort Jr., M.D., Ph.D., of the Federal University of Sao Paulo, Brazil, and colleagues examined the affected retinal layers in infants with congenital Zika syndrome ...

Two Brazilian studies show new discoveries related to Zika virus

October 12, 2016
A Brazilian study shows that infection of a pregnant woman by Zika virus may represent a risk to the baby's neurological development even when it occurs only a few days before the mother gives birth.

Zika and glaucoma linked for first time in new study

November 30, 2016
A team of researchers in Brazil and at the Yale School of Public Health has published the first report demonstrating that the Zika virus can cause glaucoma in infants who were exposed to the virus during gestation.

Recommended for you

Study indicates proof of concept for using a surrogate liquid biopsy to provide genetic profile of retinoblastoma tumors

October 12, 2017
Retinoblastoma is a tumor of the retina that generally affects children under 5 years of age. If not diagnosed early, retinoblastoma may result in loss of one or both eyes and can be fatal. Unlike most cancers that are diagnosed ...

Farsighted children struggle with attention, study finds

October 10, 2017
Farsighted preschoolers and kindergartners have a harder time paying attention and that could put them at risk of slipping behind in school, a new study suggests.

New drug reduces rate of progression of incurable eye disease

October 4, 2017
An international study including researchers from the Centre for Eye Research Australia (CERA) has found a way to slow the progression of dry age-related macular degeneration (AMD) - one of the most common causes of vision ...

Gene therapy shows promise for reversing blindness

October 2, 2017
Most causes of untreatable blindness occur due to loss of the millions of light sensitive photoreceptor cells that line the retina, similar to the pixels in a digital camera.

Discovery provides glimmer of hope to prevent blindness

September 27, 2017
Macquarie University researchers have discovered that a naturally occurring protein in the body protects the eye from the common eye disease glaucoma, and which is particularly sensitive to oxidation through environmental ...

Coming soon: Glaucoma self-care, from home?

September 23, 2017
(HealthDay)—For many glaucoma patients, repeat trips to a doctor's office to check on their eyes can be a real pain.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.