High HCV cure rates in HIV coinfection cases at urban clinic

High HCV cure rates in HIV coinfection cases at urban clinic

(HealthDay)—For patients in an urban clinic with hepatitis C virus (HCV) with HIV coinfection, HCV treatment is effective with standardized nurse/pharmacist support, according to a study published online June 13 in Hepatology.

Oluwaseun Falade-Nwulia, M.B.B.S., M.P.H., from the Johns Hopkins University School of Medicine in Baltimore, and colleagues examined HCV treatment outcomes among 255 HCV coinfected patients (88 percent black) initiating direct-acting antivirals between February 2014 and March 2016 in an urban clinic. Patients received standardized HIV nurse/pharmacist support, which included telephone calls and nurse visits.

The researchers found that 60 percent of participants had significant fibrosis and 30 percent had received treatment for HCV. Ninety-one percent of patients received ledipasvir/sofosbuvir with or without ribavirin and received 12 weeks of treatment. The sustained virologic response rate was 97 percent, with no variation by race (black and non-black, 96 and 97 percent, respectively), history of drug use, alcohol use, or psychiatric diagnosis.

"HCV treatment was highly effective among HIV-infected patients who received care within an integrated / adherence support program," the authors write. "These results suggest that race and psychosocial comorbidity may not be barriers to HCV elimination."


Explore further

Investigational dose of oral interferon-free treatment can cure hepatitis C in children

More information: Abstract
Full Text (subscription or payment may be required)
Journal information: Hepatology

Copyright © 2017 HealthDay. All rights reserved.

Citation: High HCV cure rates in HIV coinfection cases at urban clinic (2017, June 16) retrieved 20 January 2021 from https://medicalxpress.com/news/2017-06-high-hcv-hiv-coinfection-cases.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
0 shares

Feedback to editors

User comments